Extracellular miRNAs: from biomarkers to mediators of physiology and disease

MA Mori, RG Ludwig, R Garcia-Martin, BB Brandão… - Cell metabolism, 2019 - cell.com
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …

The evolutionary origin of plant and animal microRNAs

Y Moran, M Agron, D Praher, U Technau - Nature ecology & evolution, 2017 - nature.com
MicroRNAs (miRNAs) are a unique class of short endogenous RNAs, which have become
known in the past few decades as major players in gene regulation at the post …

Diatom molecular research comes of age: model species for studying phytoplankton biology and diversity

A Falciatore, M Jaubert, JP Bouly, B Bailleul… - The Plant …, 2020 - academic.oup.com
Diatoms are the world's most diverse group of algae, comprising at least 100,000 species.
Contributing~ 20% of annual global carbon fixation, they underpin major aquatic food webs …

Targeted CRISPR‐Cas9‐based gene knockouts in the model brown alga Ectocarpus

Y Badis, D Scornet, M Harada, C Caillard… - New …, 2021 - Wiley Online Library
Brown algae are an important group of multicellular eukaryotes, phylogenetically distinct
from both the animal and land plant lineages. Ectocarpus has emerged as a model …

Red macroalgae in the genomic era

M Borg, SA Krueger‐Hadfield, C Destombe… - New …, 2023 - Wiley Online Library
Rhodophyta (or red algae) are a diverse and species‐rich group that forms one of three
major lineages in the Archaeplastida, a eukaryotic supergroup whose plastids arose from a …

[图书][B] The evolution of multicellularity

MD Herron, PL Conlin, WC Ratcliff - 2022 - books.google.com
Among the most important innovations in the history of life is the transition from single-celled
organisms to more complex, multicellular organisms. Multicellularity has evolved repeatedly …

Regulation of cholesterol biosynthesis and lipid metabolism: A microRNA management perspective

A Bhattarai, EM Likos, CM Weyman, GC Shukla - Steroids, 2021 - Elsevier
Cellular disruption of lipid and cholesterol metabolism results in pathological processes
linked to metabolic and cardiovascular diseases. Classically, at the transcription stages, the …

Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

FM Waldron, GN Stone, DJ Obbard - PLoS Genetics, 2018 - journals.plos.org
RNA interference (RNAi)-related pathways target viruses and transposable element (TE)
transcripts in plants, fungi, and ecdysozoans (nematodes and arthropods), giving protection …

Too many false targets for microRNAs: challenges and pitfalls in prediction of miRNA targets and their gene ontology in model and non‐model organisms

A Fridrich, Y Hazan, Y Moran - Bioessays, 2019 - Wiley Online Library
Short (“seed”) or extended base pairing between microRNAs (miRNAs) and their target
RNAs enables post‐transcriptional silencing in many organisms. These interactions allow …

Engineering microalgae: transition from empirical design to programmable cells

Y Lu, X Zhang, H Lin, A Melis - Algal Biotechnology, 2023 - cabidigitallibrary.org
Domesticated microalgae hold great promise for the sustainable provision of various
bioresources for human domestic and industrial consumption. Efforts to exploit their potential …