Virus-induced immunosuppression in chickens

IM Gimeno, KA Schat - Avian diseases, 2018 - meridian.allenpress.com
SUMMARY A healthy immune system is a cornerstone for poultry production. Any factor
diminishing the immune responses will affect production parameters and increase cost …

Interferons and their receptors in birds: a comparison of gene structure, phylogenetic analysis, and cross modulation

H Zhou, S Chen, M Wang, A Cheng - International Journal of Molecular …, 2014 - mdpi.com
Interferon may be thought of as a key, with the interferon receptor as the signal lock:
Crosstalk between them maintains their balance during viral infection. In this review, the …

Neoplastic diseases

V Nair, I Gimeno, J Dunn, G Zavala… - Diseases of …, 2020 - Wiley Online Library
This chapter deals primarily with the three most economically important virus‐induced
transmissible neoplastic diseases of poultry, namely: the herpesvirus‐induced Marek's …

In vivo administration of ligands for chicken toll-like receptors 4 and 21 induces the expression of immune system genes in the spleen

MS Paul, AI Mallick, K Haq, S Orouji… - Veterinary Immunology …, 2011 - Elsevier
Toll-like receptors (TLRs) are a group of conserved proteins that play an important role in
pathogen recognition in addition to the initiation and regulation of innate and adaptive …

The differential antiviral activities of chicken interferon α (ChIFN-α) and ChIFN-β are related to distinct interferon-stimulated gene expression

H Qu, L Yang, S Meng, L Xu, Y Bi, X Jia, J Li, L Sun… - PLoS …, 2013 - journals.plos.org
Chicken interferon α (ChIFN-α) and ChIFN-β are type I IFNs that are important antiviral
cytokines in the innate immune system. In the present study, we identified the virus-induced …

Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken

S Sachan, S Ramakrishnan, A Annamalai, BK Sharma… - Vaccine, 2015 - Elsevier
Abstract Resiquimod (R-848), an imidazoquinoline compound, is a potent synthetic Toll-like
receptor (TLR) 7 agonist. Although the solitary adjuvant potential of R-848 is well …

[HTML][HTML] Differential expression of Toll-like receptor genes in lymphoid tissues between Marek's disease virus-infected and noninfected chickens

H Jie, L Lian, LJ Qu, JX Zheng, ZC Hou, GY Xu… - Poultry science, 2013 - Elsevier
Toll-like receptors (TLR) are trans-membrane sensors recognizing invading microbes. Toll-
like receptors play a central role in initiating immune responses against several pathogens …

Immune escape of avian oncogenic Marek's disease herpesvirus and antagonistic host immune responses

ZJ Zhu, M Teng, Y Liu, FJ Chen, Y Yao, EZ Li, J Luo - npj Vaccines, 2024 - nature.com
Marek's disease virus (MDV) is a highly pathogenic and oncogenic alpha herpesvirus that
causes Marek's disease (MD), which is one of the most important immunosuppressive and …

Effects of administration of probiotic lactobacilli on immunity conferred by the herpesvirus of turkeys vaccine against challenge with a very virulent Marek's disease …

J Bavananthasivam, M Alizadeh, J Astill, N Alqazlan… - Vaccine, 2021 - Elsevier
Several vaccines have been used to control Marek's disease (MD) in chickens. However, the
emergence of new strains of Marek's disease virus (MDV) imposes a threat to vaccine …

In ovo HVT vaccination enhances cellular responses at hatch and addition of poly I: C offers minimal adjuvant effects

AC Boone, RR Kulkarni, AL Cortes, T Villalobos… - Vaccine, 2023 - Elsevier
In ovo vaccination with herpesvirus of turkey (HVT) hastens immunocompetence in chickens
and the recommended dose (RD) of 6080 plaque-forming-units (PFU) offers the most …