The conserved Aurora family of protein kinases have emerged as crucial regulators of
mitosis and cytokinesis. Despite their high degree of homology, Aurora A and B have very …

Abstract Members of the Aurora/Ipl1p family of mitotically regulated serine/threonine kinases
are emerging as key regulators of chromosome segregation and cytokinesis. Proper …

Genetic and biochemical studies in lower eukaryotes have identified several proteins that
ensure accurate segregation of chromosomes. These include the Drosophila aurora and …

Diploid cells of budding yeast produce haploid cells through the developmental program of
sporulation, which consists of meiosis and spore morphogenesis. DNA microarrays …

The centrosomes are thought to maintain genomic stability through the establishment of
bipolar spindles during cell division, ensuring equal segregation of replicated chromosomes …

A centrosomal serine/threonine kinase, AIK13/breast tumor amplified kinase/aurora2, which
was recently identified as an oncogene, shows high amino acid identity with chromosome …

During the past five years, a growing number of serine-threonine kinases highly
homologous to the Saccharomyces cerevisiae Ipl1p kinase have been isolated in various …

We earlier isolated cDNAs encoding novel human protein kinases AIK and AIK2 sharing
high amino acid sequence identities with Drosophila Aurora and Saccharomyces cerevisiae …

Aurora2 is a cell cycle regulated serine/threonine protein kinase which is overexpressed in
many tumor cell lines. We demonstrate that Aurora2 is regulated by phosphorylation in a cell …

Here, we report on the identification of nucleolar spindle–associated protein (NuSAP), a
novel 55-kD vertebrate protein with selective expression in proliferating cells. Its mRNA and …