Cancer stem cells (CSCs) are a distinct subpopulation of tumor cells with stem cell-like
features. Able to initiate and sustain tumor growth and mostly resistant to anti-cancer …

Significance: The transcription factor NRF2 (NF-E2-related factor 2) plays an important role
as a master regulator of the cellular defense system by activating transcriptional programs of …

ABSTRACT Herpes simplex virus 1 (HSV-1) is a DNA virus belonging to the family
Herpesviridae. HSV-1 infection causes severe neurological disease in the central nervous …

While apolipoprotein E (apoE) expression by myeloid cells is recognized to control
inflammation, whether such benefits can be communicated via extracellular vesicles is not …

Colorectal cancer (CRC) is a severe threat to human health. Ginsenosides such as
ginsenoside Rh4 have been widely studied in the antitumor field. Here, we investigated the …

Objectives Developing novel therapeutic approaches to defeat chemoresistance is the major
goal of ovarian cancer research. Induction of ferroptosis has shown promising antitumor …

Our previous study showed that sodium arsenite (200 mg/L) affected the nervous system
and induced motor neuron development via the Sonic hedgehog pathway in zebrafish …

Emerging evidence shows that oral squamous cell carcinoma (OSCC) invasiveness can be
attributed to a small subpopulation of cancer stem cells (CSCs) in the bulk of the tumor …

Abstract Background and Purpose The low efficacy of mesenchymal stem cells (MSCs) has
restricted their application in the treatment of liver disease. Emerging evidence suggested …

Introduction: The PD-1/PD-L1 axis is hijacked by lung adenocarcinoma (LUAD) cells to
escape immune surveillance. PD-L1 expression in LUAD is affected, among others, by the …