Regulatory T cells (Treg) play a critical role in immune homeostasis by suppressing several
aspects of the immune response. Herein, Glycoprotein A repetitions predominant (GARP) …

Peptides provide promising application prospects for clinical therapy with their higher
bioactivity and specificity. However, the rapid degradation and short half-life hinder the …

Sarcomas are mesenchymal cancers with poor prognosis, representing about 20% of all
solid malignancies in children, adolescents, and young adults. Radio-and chemoresistance …

Abstract Background and Objective Type 2 diabetes (T2D)‐associated periodontitis is
severe and refractory in many cases. Considered an inflammatory disease, T2D …

Background To analyze and identify the circular RNAs (circRNAs) involved in promoting the
osteogenic differentiation of human bone mesenchymal stem cells (hBMSCs) on titanium by …

Multipotent mesenchymal stromal cells (MSCs) have emerged as a promising cell therapy in
regenerative medicine and for autoimmune/inflammatory diseases. However, a main hurdle …

Although many surgical or non-operative therapies have been developed to treat Achilles
tendon injuries, the prognosis of which is often unsatisfactory. Recently, biologic approaches …

Bone regeneration is a significant and crucial health issue worldwide. Tissue
bioengineering has shown itself to be the best substitute for common clinical treatment of …

Although many surgical or non-operative therapies have been developed to treat 14 Achilles
tendon injuries, the prognosis of which is often unsatisfactory. Recently, 15 biologic …

During atrophic nonunion, Wnt signaling pathway is inhibited, resulting in inhibition of BMSC
osteogenic differentiation. TGF-β regulates growth and development of the body. However …