Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by a combination of
genetic and environmental factors. Genetic evidences depict a complex network comprising …

Atopic dermatitis (AD) is a chronic inflammatory skin disease with specific genetic and
immunological mechanisms. The rapid development of new techniques in molecular biology …

Abstract Background IL4/IL4RA pathway plays an important role in atopy and asthma.
Different polymorphisms in IL4 and IL4RA genes have been described. Particularly,-33C> T …

5. Pascual M, Davila I, Isidoro-Garcia M, Lorente F. Epigenetic aspects of the allergic
diseases. Front Biosci (Schol Ed) 2010; 2: 815-24. 6. Jabara HH, Fu SM, Geha RS, Vercelli …

Abstract Background Interleukin 4 (IL4) is a key cytokine that regulates the inflammatory
cascade in bronchial asthma. We investigated the association between the IL4 and IL4R …

What is known and Objective: Montelukast, a cysteinyl leukotriene receptor 1 antagonist, is
safe and efficacious in patients with asthma. The mechanisms underlying the significant …

To the Editor: Allergic asthma is a multifactorial disorder in which activation and
differentiation of B lymphocytes toward the production of IgE play an essential role. In these …

Introduction IL4 pathway is known to upregulate IgE mediated immune responses and
responsible for the manifestation of Atopic disorders. The current study was aimed to …

The combination of genetic susceptibility and environmental factors can induce allergic
sensitization and subsequent local inflammation, resulting in atopic dermatitis (AD). Sister …

Background and objective. A variety of cytokines are involved in the incidence and
development of bronchial asthma. This study was designed to reveal the relationship among …