In many parts of the world, human-mediated environmental change is depleting biodiversity
faster than it can be characterized, while invasive species cause agricultural damage …

It has been over a decade since the first publication of a method dedicated entirely to
mapping long-reads. The distinctive characteristics of long reads resulted in methods …

As structure prediction methods are generating millions of publicly available protein
structures, searching these databases is becoming a bottleneck. Foldseek aligns the …

Highly accurate structure prediction methods are generating an avalanche of publicly
available protein structures. Searching through these structures is becoming the main …

Innovations in Next-Generation Sequencing are enabling generation of DNA sequence data
at ever faster rates and at very low cost. For example, the Illumina NovaSeq 6000 sequencer …

Motivation Recent advances in sequencing technologies promise ultra-long reads of∼ 100
kb in average, full-length mRNA or cDNA reads in high throughput and genomic contigs …

To the Editor—The cloning and subsequent engineering of fluorescent proteins (FPs) has
revolutionized methods in biological research1, 2. There are now thousands of FPs …

Background DNA barcodes are a useful tool for discovering, understanding, and monitoring
biodiversity which are critical tasks at a time of rapid biodiversity loss. However, widespread …

Domain-specific hardware accelerators Page 1 48 COMMUNICATIONS OF THE ACM | JULY
2020 | VOL. 63 | NO. 7 contributed articles FROM THE SIMPLE embedded processor in your …

Genome sequence analysis has enabled significant advancements in medical and scientific
areas such as personalized medicine, outbreak tracing, and the understanding of evolution …