The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

The insulin granule was previously thought of as merely a container, but accumulating
evidence suggests that it also acts as a signaling node. Regulatory pathways intersect at but …

The secretory prohormone chromogranin A (CHGA) is overexpressed in essential
hypertension, a complex trait with genetic predisposition, while its catecholamine release …

The dense-core secretory granule is a key organelle for secretion of hormones and
neuropeptides in endocrine cells and neurons, in response to stimulation. Cholesterol and …

The presence of activin A and its effects have previously been documented in the adrenal
gland, particularly in the human fetal adrenal gland and the rat adrenal gland. The primary …

The chromogranins A (CgA) and B (CgB) and secretogranin II (SgII) constitute the main
members of a family of uniquely acidic secretory proteins in elements of the diffuse …

Background. Neuroendocrine tumors (NETs) are characterized by having behavior and
prognosis that depend upon tumor histology, primary site, staging, and proliferative index …

Chromogranins/secretogranins or granins are a class of acidic, secretory proteins that occur
in endocrine, neuroendocrine, and neuronal cells. Granins are the precursors of several …

The endoplasmic reticulum (ER) is a highly dynamic network of membranes. Here, we
combine live-cell microscopy with in situ cryo–electron tomography to directly visualize ER …

It is increasingly clear that inflammatory diseases and cancers are influenced by cleavage
products of the pro-hormone chromogranin A (CgA), such as the 21-amino acids long …