[HTML][HTML] Injectable long-acting ivacaftor-loaded poly (lactide-co-glycolide) microparticle formulations for the treatment of cystic fibrosis: in vitro characterization and in …

DS Nakhla, AI Mekkawy, YW Naguib, AD Silva… - International journal of …, 2024 - Elsevier
Optimizing a sustained-release drug delivery system for the treatment of cystic fibrosis (CF)
is crucial for decreasing the dosing frequency and improving patients' compliance with the …

[HTML][HTML] Integration of network pharmacology and molecular docking technology reveals the mechanism of the herbal pairing of Codonopsis Pilosula (Franch.) Nannf …

J Xu, Z Zhang, K Zhou, Y Li, J Wan… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: The herbal pairing of Dangshen (DS)[Codonopsis pilosula (Franch.) Nannf.]
and Huangqi (HQ)[Astragalus membranaceus (Fisch.) Bge.](DHP) is a traditional Chinese …

Selective androgen receptor modulator microparticle formulation reverses muscle hyperalgesia in a mouse model of widespread muscle pain

JB Lesnak, DS Nakhla, AN Plumb, A McMillan, S Saha… - Pain, 2023 - journals.lww.com
Chronic pain is a significant health problem associated with disability and reduced quality of
life. Current management of chronic pain is inadequate with only modest effects of …

The MEK 1/2 inhibitor PD98059 exhibits synergistic anti-endometrial cancer activity with paclitaxel in vitro and enhanced tissue distribution in vivo when formulated …

K Wiwatchaitawee, AI Mekkawy, JC Quarterman… - Drug delivery and …, 2021 - Springer
Endometrial cancer is the most common gynecological cancer that affects the female
reproductive organs. The standard therapy for EC for the past two decades has been …

[HTML][HTML] Select Androgen Receptor Modulator Microparticle Formulation Reverses Muscle Hyperalgesia in Mouse Model of Widespread Muscle Pain

J Lesnak, D Nakhla, A Salem, KA Sluka - The journal of pain, 2022 - Elsevier
There is a need for the generation of non-opioid analgesics for chronic pain. The analgesic
effects of testosterone have been demonstrated in preclinical and clinical studies. However …

Sex, Drugs, and Physical Activity: Their Role in the Protection Against and Production of Muscle Pain

JB Lesnak - 2022 - search.proquest.com
Chronic pain is a significant health care issue affecting over 100 million Americans with
musculoskeletal pain prevalent in 13-47% of the population. Musculoskeletal pain …

Mek1/2 inhibitor-loaded microparticle formulation

AK Salem, R Felder, YWN Ibrahim - US Patent App. 17/221,532, 2021 - Google Patents
US20210361578A1 - Mek1/2 inhibitor-loaded microparticle formulation - Google Patents
US20210361578A1 - Mek1/2 inhibitor-loaded microparticle formulation - Google Patents …

Poly (diaminosulfide) particle-based vaccine

AK Salem, EI Wafa, SM Geary, NB Bowden… - US Patent …, 2024 - Google Patents
US11904006B2 - Poly(diaminosulfide) particle-based vaccine - Google Patents US11904006B2
- Poly(diaminosulfide) particle-based vaccine - Google Patents Poly(diaminosulfide) …

MEK1/2 INHIBITOR-LOADED MICROPARTICLE FORMULATION

AK Salem, R Felder… - US Patent App. 18 …, 2024 - freepatentsonline.com
MEK1/2 INHIBITOR-LOADED MICROPARTICLE FORMULATION - University of Iowa
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The use of nanoparticles in treatment of glioblastoma

K Wiwatchaitawee - 2021 - search.proquest.com
The central nervous system has a series of barriers to protect itself from exogenous
pathogens and neurotoxic molecules. The most essential part of these protective barriers is …