Computation through neural population dynamics

S Vyas, MD Golub, D Sussillo… - Annual review of …, 2020 - annualreviews.org
Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

Physiological markers of motor inhibition during human behavior

J Duque, I Greenhouse, L Labruna, RB Ivry - Trends in neurosciences, 2017 - cell.com
Transcranial magnetic stimulation (TMS) studies in humans have shown that many
behaviors engage processes that suppress excitability within the corticospinal tract …

Flexible sensorimotor computations through rapid reconfiguration of cortical dynamics

ED Remington, D Narain, EA Hosseini, M Jazayeri - Neuron, 2018 - cell.com
Neural mechanisms that support flexible sensorimotor computations are not well
understood. In a dynamical system whose state is determined by interactions among …

Independence of movement preparation and movement initiation

AM Haith, J Pakpoor, JW Krakauer - Journal of Neuroscience, 2016 - Soc Neuroscience
Initiating a movement in response to a visual stimulus takes significantly longer than might
be expected on the basis of neural transmission delays, but it is unclear why. In a visually …

The science and engineering behind sensitized brain-controlled bionic hands

C Pandarinath, SJ Bensmaia - Physiological Reviews, 2022 - journals.physiology.org
Advances in our understanding of brain function, along with the development of neural
interfaces that allow for the monitoring and activation of neurons, have paved the way for …

Integrated neural dynamics of sensorimotor decisions and actions

D Thura, JF Cabana, A Feghaly, P Cisek - PLoS biology, 2022 - journals.plos.org
Recent theoretical models suggest that deciding about actions and executing them are not
implemented by completely distinct neural mechanisms but are instead two modes of an …

Initial conditions combine with sensory evidence to induce decision-related dynamics in premotor cortex

PO Boucher, T Wang, L Carceroni, G Kane… - Nature …, 2023 - nature.com
We used a dynamical systems perspective to understand decision-related neural activity, a
fundamentally unresolved problem. This perspective posits that time-varying neural activity …

Neural population dynamics during reaching are better explained by a dynamical system than representational tuning

JA Michaels, B Dann… - PLoS computational …, 2016 - journals.plos.org
Recent models of movement generation in motor cortex have sought to explain neural
activity not as a function of movement parameters, known as representational models, but as …

Latent factors and dynamics in motor cortex and their application to brain–machine interfaces

C Pandarinath, KC Ames, AA Russo… - Journal of …, 2018 - Soc Neuroscience
In the 1960s, Evarts first recorded the activity of single neurons in motor cortex of behaving
monkeys. In the 50 years since, great effort has been devoted to understanding how single …

Multiscale low-dimensional motor cortical state dynamics predict naturalistic reach-and-grasp behavior

H Abbaspourazad, M Choudhury, YT Wong… - Nature …, 2021 - nature.com
Motor function depends on neural dynamics spanning multiple spatiotemporal scales of
population activity, from spiking of neurons to larger-scale local field potentials (LFP). How …