[HTML][HTML] Biofilms: Understanding the structure and contribution towards bacterial resistance in antibiotics

P Shree, CK Singh, KK Sodhi, JN Surya… - Medicine in …, 2023 - Elsevier
The biofilm is a bacterial colony wrapped in an auto-produced polymer matrix of
polysaccharides, proteins, and DNA. Bacterial biofilms cause persistent infections because …

An explorative review on advanced approaches to overcome bacterial resistance by curbing bacterial biofilm formation

F Mohamad, RR Alzahrani, A Alsaadi… - Infection and Drug …, 2023 - Taylor & Francis
The continuous emergence of multidrug-resistant pathogens evoked the development of
innovative approaches targeting virulence factors unique to their pathogenic cascade …

Microbial resistance to antibiotics and effective antibiotherapy

AA Chiș, LL Rus, C Morgovan, AM Arseniu, A Frum… - Biomedicines, 2022 - mdpi.com
Currently, the efficacy of antibiotics is severely affected by the emergence of the
antimicrobial resistance phenomenon, leading to increased morbidity and mortality …

A comprehensive guide on screening and selection of a suitable AMP against biofilm-forming bacteria

A Anurag Anand, A Amod, S Anwar… - Critical Reviews in …, 2023 - Taylor & Francis
Lately, antimicrobial resistance (AMR) is increasing at an exponential rate making it
important to search alternatives to antibiotics in order to combat multi-drug resistant (MDR) …

Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections

NN Tran, T Morrisette, SCJ Jorgensen… - … : The Journal of …, 2023 - Wiley Online Library
Staphylococcus aureus is a major cause of nosocomial and community‐acquired infections
and contributes to significant increase in morbidity and mortality especially when associated …

Ecology and evolutionary biology of hindering phage therapy: The phage tolerance vs. phage resistance of bacterial biofilms

ST Abedon - Antibiotics, 2023 - mdpi.com
As with antibiotics, we can differentiate various acquired mechanisms of bacteria-mediated
inhibition of the action of bacterial viruses (phages or bacteriophages) into ones of tolerance …

Finding novel AMPs secreted from the human microbiome as potent antibacterial and antibiofilm agents and studying their synergistic activity with Ag NCs

A Singh, A Amod, V Mulpuru, N Mishra… - ACS Applied Bio …, 2023 - ACS Publications
Due to the enhanced resistance of bacteria to antibiotics, researchers always try to find
effective alternatives to treat drug-resistant bacterial infections. In this context, we have …

Structurally diverse G-quadruplexes as the noncanonical nucleic acid drug target for live cell imaging and antibacterial study

BX Zheng, J Yu, W Long, KH Chan… - Chemical …, 2023 - pubs.rsc.org
The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid
sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …

Nanomaterials for delivering antibiotics in the therapy of pneumonia

J Tang, Q Ouyang, Y Li, P Zhang, W Jin, S Qu… - International Journal of …, 2022 - mdpi.com
Bacterial pneumonia is one of the leading causes of death worldwide and exerts a
significant burden on health-care resources. Antibiotics have long been used as first-line …

Biofilm Formation of Helicobacter pylori in Both Static and Microfluidic Conditions Is Associated With Resistance to Clarithromycin

P Krzyżek, P Migdał, R Grande… - Frontiers in cellular and …, 2022 - frontiersin.org
It is widely accepted that production of biofilm is a protective mechanism against various
type of stressors, including exposure to antibiotics. However, the impact of this structure on …