Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Advances in the application of magnetic nanoparticles for sensing

L Gloag, M Mehdipour, D Chen, RD Tilley… - Advanced …, 2019 - Wiley Online Library
Magnetic nanoparticles (MNPs) are of high significance in sensing as they provide viable
solutions to the enduring challenges related to lower detection limits and nonspecific effects …

Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers

C Liu, J Zhao, F Tian, L Cai, W Zhang, Q Feng… - Nature biomedical …, 2019 - nature.com
Non-invasive assays for early cancer screening are hampered by challenges in the isolation
and profiling of circulating biomarkers. Here, we show that surface proteins from serum …

Magnetic nanoparticles for cancer theranostics: Advances and prospects

X Li, W Li, M Wang, Z Liao - Journal of Controlled Release, 2021 - Elsevier
Cancer is one of the leading causes of mortality worldwide. Nanoparticles have been
broadly studied and emerged as a novel approach in diagnosis and treatment of tumors …

Advances in biosensors and diagnostic technologies using nanostructures and nanomaterials

EC Welch, JM Powell, TB Clevinger… - Advanced Functional …, 2021 - Wiley Online Library
Nanoscale materials have unique properties that make them especially useful for
biomedical diagnostic applications. Recent developments in nanoengineering have resulted …

Challenges and solutions in developing ultrasensitive biosensors

Y Wu, RD Tilley, JJ Gooding - Journal of the American Chemical …, 2018 - ACS Publications
This Perspective focuses on the latest strategies and challenges for the development of
bioanalytical sensors with sub-picomolar detection limits. Achieving sub-picomolar detection …

Single-cell analysis targeting the proteome

M Labib, SO Kelley - Nature Reviews Chemistry, 2020 - nature.com
The existence of cellular heterogeneity and its central relevance to biological phenomena
provides a strong rationale for a need for analytical methods that enable analysis at the …

[HTML][HTML] Biomimetic platelet membrane-coated nanoparticles for targeted therapy

H Han, R Bartolo, J Li, MA Shahbazi… - European Journal of …, 2022 - Elsevier
The development of cell membrane-modified biomimetic nanoparticles has extensively
increased during the past years due to their exceptional biocompatibility, evasion from the …

Single-cell sequencing: a promising approach for uncovering the mechanisms of tumor metastasis

Y Han, D Wang, L Peng, T Huang, X He… - Journal of hematology & …, 2022 - Springer
Single-cell sequencing (SCS) is an emerging high-throughput technology that can be used
to study the genomics, transcriptomics, and epigenetics at a single cell level. SCS is widely …

Microscale acoustic streaming for biomedical and bioanalytical applications

W Wei, Y Wang, Z Wang, X Duan - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Over the past few decades, acoustofluidics, one of the branches of microfluidics, has rapidly
developed as a multidisciplinary cutting edge research topic, covering many biomedical and …