The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

Epigenetic regulatory mechanisms, including DNA methylation, histone modification,
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …

A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …

Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

Parkinson's disease is a common neurodegenerative disorder in which gastrointestinal
symptoms may appear prior to motor symptoms. The gut microbiota of patients with …

Dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …

Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by motor dysfunction. Growing evidence has demonstrated that gut dysbiosis …

The human intestinal microbiome substantially affects human health and resistance to
infections in its dynamic composition and varying release of microbial-derived metabolites …

Background Parkinson's disease (PD) is a neurodegenerative disorder with no absolute
cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the …

The human microbiota comprises trillions of symbiotic microorganisms and is involved in
regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis …