Importance Cancer-related fatigue (CRF) remains one of the most prevalent and
troublesome adverse events experienced by patients with cancer during and after therapy …

Ample evidence suggests that sleep and pain are related. However, many questions remain
about the direction of causality in their association, as well as mechanisms that may account …

Objective: Pain, depression, and fatigue function as a symptom cluster and thus may share
common risk factors. Interpersonal relationships clearly influence health, suggesting that …

Objectives: A relationship between sleep and pain is well established. A better
understanding of the mechanisms that link sleep and pain intensity is urgently needed to …

Individuals with cancer are disproportionately affected by sleep disturbance and insomnia
relative to the general population. These problems can be a consequence of the …

Background Insomnia is a common and debilitating disorder experienced by cancer
survivors. Although cancer survivors express a preference for using nonpharmacological …

Study Objectives: Osteoarthritis pain affects more than half of all older adults, many of whom
experience co-morbid sleep disturbance. Pain initiates and exacerbates sleep disturbance …

Pain, fatigue, sleep disturbance, and depression are common and frequently co-occurring
symptoms in oncology patients. This symptom cluster is often attributed to the release of …

Sleep disturbances in midlife women are common and have been associated with the
menopause transition itself, symptoms of hot flashes, anxiety and depressive disorders …

Background: Cancer-related fatigue (CRF) often co-occurs with sleep disturbance and is
one of the most pervasive toxicities resulting from cancer and its treatment. We and other …