Permeation enhancers in transdermal drug delivery: Benefits and limitations

A Kováčik, M Kopečná, K Vávrová - Expert opinion on drug delivery, 2020 - Taylor & Francis
Introduction: Transdermal drug delivery has several clinical benefits over conventional
routes of drug administration. To open the transdermal route for a wider range of drugs …

[HTML][HTML] Development of nanoparticle-delivery systems for antiviral agents: A review

R Delshadi, A Bahrami, DJ McClements… - Journal of Controlled …, 2021 - Elsevier
The COVID-19 pandemic has resulted in unprecedented increases in sickness, death,
economic disruption, and social disturbances globally. However, the virus (SARS-CoV-2) …

Strat-M® synthetic membrane: Permeability comparison to human cadaver skin

A Haq, B Goodyear, D Ameen, V Joshi… - International journal of …, 2018 - Elsevier
The aim of this work was to investigate the correlation of permeation behavior of transdermal
formulations through a novel synthetic membrane (Strat-M® EMD Millipore, MA) and human …

Penetration of nanoparticles and nanomaterials in the skin: fiction or reality?

B Baroli - Journal of pharmaceutical sciences, 2010 - Elsevier
The advent of nanotechnological products in the market, while holding great promise, is
raising concerns in consumers. Therefore, this contribution will attempt to compare different …

Transdermal drug delivery in vitro using diffusion cells

L Bartosova, J Bajgar - Current medicinal chemistry, 2012 - ingentaconnect.com
The assessment of percutaneous absorption of molecules is a very important step in the
evaluation of any dermal or transdermal drug delivery system. In order to perform …

Status of terpenes as skin penetration enhancers

M Aqil, A Ahad, Y Sultana, A Ali - Drug discovery today, 2007 - Elsevier
Since its introduction, transdermal drug delivery has promised much but, in some respects
has still to deliver on that initial promise, due to inherent limitations imposed by the …

Effects of solvents and penetration enhancers on transdermal delivery of thymoquinone: Permeability and skin deposition study

A Haq, B Michniak-Kohn - Drug delivery, 2018 - Taylor & Francis
Thymoquinone (TQ) is a quinone-based phytochemical that was first identified in 1963 in
Nigella sativa (black cumin seed) by El-Dakhakhany. Based on the ideal characteristics of …

[HTML][HTML] Novel chemical permeation enhancers for transdermal drug delivery

Y Chen, P Quan, X Liu, M Wang, L Fang - Asian Journal of Pharmaceutical …, 2014 - Elsevier
Transdermal drug delivery has been accepted as a potential non-invasive route of drug
administration, with advantages of prolonged therapeutic action, decreased side effect, easy …

Effect of chemical permeation enhancers on stratum corneum barrier lipid organizational structure and interferon alpha permeability

SH Moghadam, E Saliaj, SD Wettig, C Dong… - Molecular …, 2013 - ACS Publications
The outermost layer of the skin, known as the stratum corneum (SC), is composed of dead
corneocytes embedded in an intercellular lipid matrix consisting of ceramides, free fatty …

Current status of amino acid-based permeation enhancers in transdermal drug delivery

R Pereira, SG Silva, M Pinheiro, S Reis, ML Vale - Membranes, 2021 - mdpi.com
Transdermal drug delivery (TDD) presents many advantages compared to other
conventional routes of drug administration, yet its full potential has not been achieved. The …