USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration

E Prokakis, H Bamahmoud, S Jansari… - Cell Communication and …, 2024 - Springer
Background Breast cancer (BC) is the most frequent tumor entity in women worldwide with a
high chance of therapeutic response in early-and non-metastatic disease stages. Among all …

Ubiquitin‐specific protease 22 promotes tumorigenesis and progression by an FKBP12/mTORC1/autophagy positive feedback loop in hepatocellular carcinoma

Q Ye, W Zhou, S Xu, Q Que, Q Zhan, L Zhang… - MedComm, 2023 - Wiley Online Library
Abstract Ubiquitin‐specific protease 22 (USP22) has been identified as a potential marker
for cancer stem cells in hepatocellular carcinoma (HCC). It can promote HCC stemness …

Mogrol-Mediated enhancement of radiotherapy sensitivity in Non-Small cell lung cancer: A mechanistic study

Z Yin, X Zhang, X Sun, Y Huo, N Ji… - American Journal of …, 2024 - journals.physiology.org
Objective: Investigate Mogrol's impact on NSCLC radiosensitivity and underlying
mechanisms using various methods including assays, bioinformatics, and xenograft models …

USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity

X Kuang, A Salinger, F Benavides, WJ Muller… - Plos one, 2024 - journals.plos.org
The Ubiquitin Specific Peptidase 22 (USP22), a component of the Spt-Ada-Gcn5
Acetyltransferase (SAGA) histone modifying complex, is overexpressed in multiple human …

2 型糖尿病患者血清E 盒锌指蛋白1 和泛素化特异性蛋白酶22 表达水平与糖脂代谢及胰岛素抵抗的关系.

于冲, 施毕, 陆雯, 廖蔼东… - Chinese Journal of …, 2024 - search.ebscohost.com
目的检测2 型糖尿病患者血清E 盒锌指蛋白1 (ZEB1) 和泛素化特异性蛋白酶22 (USP22)
基因的表达水平, 分析两者与糖脂代谢及胰岛素抵抗的关系. 方法选择2020 年6 月至2023 年6 …