EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
[HTML][HTML] Mechanisms of resistance in castration-resistant prostate cancer (CRPC)
T Chandrasekar, JC Yang, AC Gao… - … andrology and urology, 2015 - ncbi.nlm.nih.gov
Despite advances in prostate cancer diagnosis and management, morbidity from prostate
cancer remains high. Approximately 20% of men present with advanced or metastatic …
cancer remains high. Approximately 20% of men present with advanced or metastatic …
Androgen receptor: structure, role in prostate cancer and drug discovery
Androgens and androgen receptors (AR) play a pivotal role in expression of the male
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate …
phenotype. Several diseases, such as androgen insensitivity syndrome (AIS) and prostate …
Androgen receptors in hormone-dependent and castration-resistant prostate cancer
AA Shafi, AE Yen, NL Weigel - Pharmacology & therapeutics, 2013 - Elsevier
Abstract In the United States, prostate cancer (PCa) is the most commonly diagnosed non-
cutaneous cancer in males and the second leading cause of cancer-related death for men …
cutaneous cancer in males and the second leading cause of cancer-related death for men …
Reduction of circular RNA Foxo3 promotes prostate cancer progression and chemoresistance to docetaxel
Z Shen, L Zhou, C Zhang, J Xu - Cancer letters, 2020 - Elsevier
Dysregulation of circular RNA Foxo3 (circFoxo3) has been reported to be involved in breast
cancer and non-small lung cancer progression. However, little is known about the role of …
cancer and non-small lung cancer progression. However, little is known about the role of …
[HTML][HTML] Diverse molecular targets for chalcones with varied bioactivities
B Zhou, C Xing - Medicinal chemistry, 2015 - ncbi.nlm.nih.gov
Natural or synthetic chalcones with different substituents have revealed a variety of
biological activities that may benefit human health. The underlying mechanisms of action …
biological activities that may benefit human health. The underlying mechanisms of action …
Advances in receptor‐mediated, tumor‐targeted drug delivery
Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …
Dissecting the expression landscape of RNA-binding proteins in human cancers
B Kechavarzi, SC Janga - Genome biology, 2014 - Springer
Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by
controlling gene expression at the post-transcriptional level. Results We explore the …
controlling gene expression at the post-transcriptional level. Results We explore the …
Biological roles of LSD1 beyond its demethylase activity
F Gu, Y Lin, Z Wang, X Wu, Z Ye, Y Wang… - Cellular and Molecular …, 2020 - Springer
It is well-established that Lysine-specific demethylase 1 (LSD1, also known as KDM1A)
roles as a lysine demethylase canonically acting on H3K4me1/2 and H3K9me1/2 for …
roles as a lysine demethylase canonically acting on H3K4me1/2 and H3K9me1/2 for …
[HTML][HTML] ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3
L Zhou, Z Song, J Hu, L Liu, Y Hou, X Zhang, X Yang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Current endocrine therapy for prostate cancer (PCa) mainly inhibits androgen/androgen
receptor (AR) signaling. However, due to increased intratumoural androgen synthesis and …
receptor (AR) signaling. However, due to increased intratumoural androgen synthesis and …