Speed scaling in multiphoton fluorescence microscopy
After over 30 years of advances, multiphoton microscopy (MPM) is now instrumental in a
wide range of in vivo biological imaging applications. However, it has, until recently …
wide range of in vivo biological imaging applications. However, it has, until recently …
Non-diffracting light wave: fundamentals and biomedical applications
The light propagation in the medium normally experiences diffraction, dispersion, and
scattering. Studying the light propagation is a century-old problem as the photons may …
scattering. Studying the light propagation is a century-old problem as the photons may …
Two-photon nanoprobes based on bioorganic nanoarchitectonics with a photo-oxidation enhanced emission mechanism
S Li, R Chang, L Zhao, R Xing, JCM van Hest… - Nature …, 2023 - nature.com
Two-photon absorption (TPA) fluorescence imaging holds great promise in diagnostics and
biomedicine owing to its unparalleled spatiotemporal resolution. However, the adaptability …
biomedicine owing to its unparalleled spatiotemporal resolution. However, the adaptability …
A positively tuned voltage indicator for extended electrical recordings in the brain
Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …
Multi-focus light-field microscopy for high-speed large-volume imaging
High-speed visualization of three-dimensional (3D) processes across a large field of view
with cellular resolution is essential for understanding living systems. Light-field microscopy …
with cellular resolution is essential for understanding living systems. Light-field microscopy …
Ultrafast two-photon fluorescence imaging of cerebral blood circulation in the mouse brain in vivo
Characterizing blood flow dynamics in vivo is critical to understanding the function of the
vascular network under physiological and pathological conditions. Existing methods for …
vascular network under physiological and pathological conditions. Existing methods for …
The mitochondrial unfolded protein response regulates hippocampal neural stem cell aging
Aging results in a decline in neural stem cells (NSCs), neurogenesis, and cognitive function,
and evidence is emerging to demonstrate disrupted adult neurogenesis in the hippocampus …
and evidence is emerging to demonstrate disrupted adult neurogenesis in the hippocampus …
Ultrafast longitudinal imaging of haemodynamics via single-shot volumetric photoacoustic tomography with a single-element detector
Techniques for imaging haemodynamics use ionizing radiation or contrast agents or are
limited by imaging depth (within approximately 1 mm), complex and expensive data …
limited by imaging depth (within approximately 1 mm), complex and expensive data …
De Novo Design of Aggregation‐Induced Emission Luminogen for Three‐Photon Fluorescence Imaging of Subcortical Structures Excited at Both NIR‐III and NIR‐IV …
S Tong, W Xu, J Zhong, M Kang, X Chen… - Advanced Functional …, 2023 - Wiley Online Library
Abstract Three‐photon fluorescence (3PF) imaging excited at 1700 nm window is an
enabling technology for visualizing deep brain structures and dynamics. Recently, the 2200 …
enabling technology for visualizing deep brain structures and dynamics. Recently, the 2200 …
[HTML][HTML] Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex
Dysfunction of gamma-aminobutyric acid (GABA) ergic circuits is strongly associated with
neurodevelopmental disorders. However, it is unclear how genetic predispositions impact …
neurodevelopmental disorders. However, it is unclear how genetic predispositions impact …