Micronucleus assay: the state of art, and future directions

S Sommer, I Buraczewska, M Kruszewski - International journal of …, 2020 - mdpi.com
During almost 40 years of use, the micronucleus assay (MN) has become one of the most
popular methods to assess genotoxicity of different chemical and physical factors, including …

Micronuclei as biomarkers of DNA damage, aneuploidy, inducers of chromosomal hypermutation and as sources of pro-inflammatory DNA in humans

M Fenech, S Knasmueller, C Bolognesi… - … Research/Reviews in …, 2020 - Elsevier
Micronuclei (MNi) are among the most widely studied biomarkers of DNA damage and
chromosomal instability in humans. They originate from chromosome fragments or intact …

Electronic nicotine-delivery systems for smoking cessation

R Auer, A Schoeni, JP Humair… - … England Journal of …, 2024 - Mass Medical Soc
Background Electronic nicotine-delivery systems—also called e-cigarettes—are used by
some tobacco smokers to assist with quitting. Evidence regarding the efficacy and safety of …

Potential uses, limitations, and basic procedures of micronuclei and nuclear abnormalities in buccal cells

O Torres-Bugarín, MG Zavala-Cerna, A Nava… - Disease …, 2014 - Wiley Online Library
The use of biomarkers as tools to evaluate genotoxicity is increasing recently. Methods that
have been used previously to evaluate genomic instability are frequently expensive …

Clinical application of micronucleus test in exfoliated buccal cells: A systematic review and metanalysis

C Bolognesi, S Bonassi, S Knasmueller… - … research/reviews in …, 2015 - Elsevier
The micronucleus assay in uncultured exfoliated buccal mucosa cells, involving minimally
invasive sampling, was successfully applied to evaluate inhalation and local exposure to …

Epicatechin and quercetin exhibit in vitro antioxidant effect, improve biochemical parameters related to metabolic syndrome, and decrease cellular genotoxicity in …

A Leyva-Soto, RA Chavez-Santoscoy, O Porras… - Food Research …, 2021 - Elsevier
Metabolic syndrome is a condition whose incidence has been increasing around the world.
It promotes a metabolic state of chronic systemic inflammation, correlated to cellular stress …

Toxicological aspects of trihalomethanes: a systematic review

L de Castro Medeiros, FLS de Alencar… - … Science and Pollution …, 2019 - Springer
Chlorine is considered the most used chemical agent for water disinfection worldwide.
However, water chlorination can lead to by-product generation which can be toxic to …

Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins …

A Nersesyan, M Fenech, C Bolognesi, M Mišík… - … Research/Reviews in …, 2016 - Elsevier
This article concerns the use of the lymphocyte cytokinesis-block micronucleus (CBMN)
assay in biomonitoring of occupational and environmental exposures to genotoxic agents …

Recommendations and quality criteria for micronucleus studies with humans

A Nersesyan, M Kundi, M Fenech, H Stopper… - … Research/Reviews in …, 2022 - Elsevier
Micronucleus (MN) analyses in peripheral blood lymphocytes and exfoliated cells from
different organs (mouth, nose, bladder and cervix) are at present the most widely used …

Micronuclei and disease–Report of HUMN project workshop at Rennes 2019 EEMGS conference

M Fenech, N Holland, M Kirsch-Volders… - … /Genetic Toxicology and …, 2020 - Elsevier
Abstract The “Micronuclei and Disease” workshop was organized by the HUMN Project
consortium and hosted by the European Environmental Mutagen and Genomics Society at …