This review aims to summarize the latest knowledge on factors, diagnosis, and treatment of
pancreatic cancer, and aims to promote further research on this under-studied malignant …

Background: The rising prevalence of obesity represents an important public health issue.
An assessment of its costs may be useful in providing recommendations for policy and …

The gastrointestinal tract has recently come to the forefront of multiple research fields. It is
now recognized as a major source of signals modulating food intake, insulin secretion and …

Purpose tumor-infiltrating immune cells are highly relevant to the progression and prognosis
of colorectal cancer (CRC). The aim of this study is to explore the immune cells and immune …

Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …

The prevalence of nonalcoholic fatty liver disease (NAFLD) is continuing to rise in many
countries, paralleling the epidemic of obesity worldwide. In the last years, the concept of …

Obesity is a global epidemic, placing socioeconomic strain on public healthcare systems,
especially within the so-called Western countries, such as Australia, United States, United …

Background & aims Although high-fat diet (HFD) could impact the composition of fecal
microbiome and their metabolites, it is still largely unknown which fecal bacteria and …

We previously demonstrated that neurotensin (NTS) induces local inflammation and
promotes tumor invasion in hepatocellular carcinoma (HCC). However, the underlying …

The neurotensin system spans across the central nervous system, to the enteric nervous
system (gut), and the periphery to govern behaviors and physiological responses that tune …