Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …

Recent advances in sequencing technologies and collaborative efforts have led to
substantial progress in identifying the genetic causes of amyotrophic lateral sclerosis (ALS) …

Amyotrophic lateral sclerosis (ALS) is an intractable disease that causes respiratory failure
leading to mortality. The main locus of ALS is motor neurons. The success of antisense …

Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration with
typical survival of only 2–5 years from diagnosis. The causes of ALS are multifactorial …

Various genetic and environmental risk factors have been implicated in the pathogenesis of
amyotrophic lateral sclerosis (ALS). Despite this, the cause of most ALS cases remains …

Prior studies have found associations between atopic dermatitis (AD) and comorbidities,
including depression, obesity, asthma, and allergic rhinitis. Although observational studies …

Psoriasis (PSO) and psoriatic arthritis (PSA) are inflammatory diseases with complex genetic
and environmental contributions. Although studies have identified environmental and …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective
vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether …

Brain vascular health appears to be critical for preventing the development of amyotrophic
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …

Background: Age-related macular degeneration (AMD) is a leading cause of blindness in
the industrialised world and is projected to affect> 280 million people worldwide by 2040 …