RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …

Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Microfluidic hydrogel microspheres have been broadly studied across a wide range of
industries and applications, and their use in the medical field, including control cells and …

In recent years, nanoparticles have evolved to a clinical modality to deliver diverse nucleic
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …

Reconstruction of bone defects, especially the critical-sized defects, with mechanical
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …

The demand for biomaterials that promote the repair, replacement, or restoration of hard and
soft tissues continues to grow as the population ages. Traditionally, smart biomaterials have …

Current therapeutic strategies such as angiogenic therapy and anti-inflammatory therapy for
treating myocardial infarction have limited success. An effective approach may benefit from …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …