[图书][B] The future of everything: The science of prediction

D Orell - 2008 - books.google.com
Hurricane Katrina, the internet stock bubble, disease outbreaks--are these predictable,
preventable events, or are we merely the playthings of chaos? A compelling, irreverent …

Impact of yeast systems biology on industrial biotechnology

D Petranovic, GN Vemuri - Journal of biotechnology, 2009 - Elsevier
Systems biology is yet an emerging discipline that aims to quantitatively describe and
predict the functioning of a biological system. This nascent discipline relies on the recent …

Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast

SA Ramsey, JJ Smith, D Orrell, M Marelli… - Nature …, 2006 - nature.com
Transcriptional noise is known to be an important cause of cellular heterogeneity and
phenotypic variation. The extent to which molecular interaction networks may have evolved …

The regulatory roles of the galactose permease and kinase in the induction response of the GAL network in Saccharomyces cerevisiae

KM Hawkins, CD Smolke - Journal of Biological Chemistry, 2006 - ASBMB
The GAL genetic switch of Saccharomyces cerevisiae exhibits an ultrasensitive response to
the inducer galactose as well as the" all-or-none" behavior characteristic of many eukaryotic …

Quantitative models of nuclear transport

A Becskei, IW Mattaj - Current opinion in cell biology, 2005 - Elsevier
Nuclear pore complexes mediate the rapid trafficking of target macromolecules between the
nucleus and the cytoplasm but exclude non-targets. Mathematical modeling helps to define …

Designing antibacterial peptides with enhanced killing kinetics

FH Waghu, S Joseph, S Ghawali, EA Martis… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are gaining attention as substitutes for antibiotics in order to
combat the risk posed by multi-drug resistant pathogens. Several research groups are …

Effects of galactose adaptation in yeast for ethanol fermentation from red seaweed, Gracilaria verrucosa

CH Ra, YJ Kim, SY Lee, GT Jeong, SK Kim - Bioprocess and biosystems …, 2015 - Springer
A total monosaccharide concentration of 39.6 g/L, representing 74.0% conversion of 53.5
g/L total carbohydrate from 80 g dw/L (8% w/v) Gracilaria verrucosa slurry, was obtained by …

Polymorphisms in the yeast galactose sensor underlie a natural continuum of nutrient-decision phenotypes

KB Lee, J Wang, J Palme, R Escalante-Chong… - PLoS …, 2017 - journals.plos.org
In nature, microbes often need to" decide" which of several available nutrients to utilize, a
choice that depends on a cell's inherent preference and external nutrient levels. While …

Multiple feedback loop design in the tryptophan regulatory network of Escherichia coli suggests a paradigm for robust regulation of processes in series

S Bhartiya, N Chaudhary… - Journal of the …, 2006 - royalsocietypublishing.org
Biological networks have evolved through adaptation in uncertain environments. Of the
different possible design paradigms, some may offer functional advantages over others …

The galactose switch in Kluyveromyces lactis depends on nuclear competition between Gal4 and Gal1 for Gal80 binding

A Anders, H Lilie, K Franke, L Kapp, J Stelling… - Journal of Biological …, 2006 - ASBMB
The Gal4 protein represents a universally functional transcription activator, which in yeast is
regulated by protein-protein interaction of its transcription activation domain with the inhibitor …