[HTML][HTML] Body fatness associations with cancer: evidence from recent epidemiological studies and future directions

SC Larsson, N Spyrou, CS Mantzoros - Metabolism, 2022 - Elsevier
This narrative review highlights current evidence linking greater body fatness to risk of
various cancers, with focus on evidence from recent large cohort studies and pooled …

Obesity and prostate cancer—microenvironmental roles of adipose tissue

A Saha, MG Kolonin, J DiGiovanni - Nature Reviews Urology, 2023 - nature.com
Obesity is known to have important roles in driving prostate cancer aggressiveness and
increased mortality. Multiple mechanisms have been postulated for these clinical …

Obesity and prostate cancer screening, incidence, and mortality in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

LM Hurwitz, N Dogbe, KH Barry… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Though obesity, measured by body mass index (BMI), is an established risk
factor for several cancer sites, there is conflicting evidence on whether obesity increases …

Actigraphy-derived measures of sleep and risk of prostate cancer in the UK Biobank

JR Freeman, PF Saint-Maurice, EL Watts… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Studies of sleep and prostate cancer are almost entirely based on self-report,
with limited research using actigraphy. Our goal was to evaluate actigraphy-measured sleep …

Aspartoacylase suppresses prostate cancer progression by blocking LYN activation

H Weng, KP Xiong, W Wang, KY Qian, S Yuan… - Military Medical …, 2023 - Springer
Background Globally, despite prostate cancer (PCa) representing second most prevalent
malignancy in male, the precise molecular mechanisms implicated in its pathogenesis …

Mechanisms of prostate cancer cells survival and their therapeutic targeting

T Pejčić, Z Todorović, S Đurašević… - International Journal of …, 2023 - mdpi.com
Prostate cancer (PCa) is today the second most common cancer in the world, with almost
400,000 deaths annually. Multiple factors are involved in the etiology of PCa, such as older …

Assessment of correlation between conventional anthropometric and imaging-derived measures of body fat composition: a systematic literature review and meta …

S Mouchti, J Orliacq, G Reeves, Z Chen - BMC medical imaging, 2023 - Springer
Background In studies of the association of adiposity with disease risk, widely used
anthropometric measures of adiposity (eg body-mass-index [BMI], waist circumference [WC] …

Genetic predisposition to metabolically unfavourable adiposity and prostate cancer risk: A Mendelian randomization analysis

A Perez‐Cornago, K Smith‐Byrne… - Cancer …, 2023 - Wiley Online Library
Background The associations of adiposity with aggressive prostate cancer risk are unclear.
Using two‐sample Mendelian randomization, we assessed the association of metabolically …

Greenspace and risk of obesity-related cancer in the UK Biobank cohort: An analysis of private residential gardens and other greenspace types

CC Odebeatu, D Darssan, C Roscoe, M Ahmed… - Science of The Total …, 2024 - Elsevier
Background Cohort studies linking greenspace exposure to a lower risk of obesity-related
cancer (ORC) are scarce. Existing evidence on site-specific cancers has predominantly …

[HTML][HTML] Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics

TA Desai, ÅK Hedman, M Dimitriou, M Koprulu… - …, 2024 - thelancet.com
Background Understanding the role of circulating proteins in prostate cancer risk can reveal
key biological pathways and identify novel targets for cancer prevention. Methods We …