Selenium and human health

MP Rayman - The Lancet, 2012 - thelancet.com
Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects,
ranging from antioxidant and anti-inflammatory effects to the production of active thyroid …

Selenium: an element for life

LH Duntas, S Benvenga - Endocrine, 2015 - Springer
This review aims to illustrate the importance of selenium (Se) for maintenance of overall
health, especially for the thyroid, immunity, and homeostasis. Furthermore, it outlines the …

Selenium in human health and disease

SJ Fairweather-Tait, Y Bao, MR Broadley… - Antioxidants & redox …, 2011 - liebertpub.com
This review covers current knowledge of selenium in the environment, dietary intakes,
metabolism and status, functions in the body, thyroid hormone metabolism, antioxidant …

Selenium in global food systems

GF Combs Jr - British journal of nutrition, 2001 - cambridge.org
Food systems need to produce enough of the essential trace element Se to provide regular
adult intakes of at least 40 μg/d to support the maximal expression of the Se enzymes, and …

Selenium exposure and the risk of type 2 diabetes: a systematic review and meta-analysis

M Vinceti, T Filippini, KJ Rothman - European journal of epidemiology, 2018 - Springer
In 2007, supplementation with the trace element selenium in a trial was unexpectedly found
to be associated with an excess risk of type 2 diabetes. Given the concerns raised by these …

Selenium, the thyroid, and the endocrine system

J Kohrle, F Jakob, B Contempré… - Endocrine reviews, 2005 - academic.oup.com
Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …

[PDF][PDF] Consequences of the diabetic status on the oxidant/antioxidant balance

D Bonnefont-Rousselot, JP Bastard… - Diabetes and …, 2000 - academia.edu
It has been shown that elevated extra-and intracellular glucose concentrations result in an
oxidative stress, which is defined as an imbalance between prooxidants and antioxidants …

Essentiality of selenium in the human body: relationship with different diseases

M Navarro-Alarcon, MC López-Martınez - Science of the Total Environment, 2000 - Elsevier
In the present review different aspects related to the essential element selenium in the
human organism are considered. A large number of human studies have been performed in …

Selenium and diabetes—evidence from animal studies

J Zhou, K Huang, XG Lei - Free Radical Biology and Medicine, 2013 - Elsevier
Whereas selenium was found to act as an insulin mimic and to be antidiabetic in earlier
studies, recent animal experiments and human trials have shown an unexpected risk of …

Selenium and metabolic disorders: an emphasis on type 2 diabetes risk

AN Ogawa-Wong, MJ Berry, LA Seale - Nutrients, 2016 - mdpi.com
Selenium (Se) is a micronutrient that maintains biological functions through the action of Se
containing proteins known as selenoproteins. Due to the known antioxidant effects of Se …