The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …

Endocrine pituitary cells are neuronlike; they express numerous voltage-gated sodium,
calcium, potassium, and chloride channels and fire action potentials spontaneously …

Nicotinic acetylcholine receptors (nAChRs) are widely distributed in the central nervous
system and have been implicated in multiple behavioral paradigms and pathological …

Methyllycaconitine, a toxin isolated from the seeds of Delphinium the right in fetal rat
hippocampal neurons, suggesting a possible brownii, inhibited acetylcholine- and anatoxin …

The diversity of neuronal nicotinic receptors (nAChRs) in addition to their possible
involvement in such pathological conditions as Alzheimer's disease have directed our …

Neuronal membrane components that bind a-bungarotoxin with high affinity can increase
intracellular levels of free calcium, demonstrating the components function as nicotinic …

Nicotinic acetylcholine receptors (AChRs) located in the postsynaptic membrane on neurons
are responsible for mediating fast, excitatory synaptic transmission. If synaptic AChRs are …

The presence of functional nicotinic acetylcholine receptors (nAChRs) on cultured neurons
of the rat olfactory bulb was evaluated using the whole-cell patch-clamp technique …

Acetylcholine-induced currents of mushroom body Kenyon cells from the honey bee Apis
mellifera were studied using the whole-cell configuration of the patch clamp technique …

One of the most abundant nicotinic receptors in the nervous system is a species that
contains the α7 gene product, rapidly desensitizes, and binds α-bungarotoxin with great …