Nanozymes are nanomaterials with catalytic properties similar to those of natural enzymes,
and they have recently been collectively identified as a class of innovative artificial enzymes …

Multicellular organisms are constantly subjected to pathogens that might be harmful.
Although insects lack an adaptive immune system, they possess highly effective anti …

Different studies corroborate a role for ceramide synthases and their downstream products,
ceramides, in modulation of apoptosis and autophagy in the context of cancer. These …

Complex molecular mechanisms define our responses to environmental stimuli. Beyond the
DNA sequence itself, epigenetic machinery orchestrates changes in gene expression …

Background Skeletal muscle is sensitive to bile acids (BA) because it expresses the TGR5
receptor for BA. Cholic (CA) and deoxycholic (DCA) acids induce a sarcopenia-like …

Selenium is an essential trace element that is essential for various metabolic processes,
protection from oxidative stress and proper functioning of the cardiovascular system. Se …

Cisplatin is an effective chemotherapeutic drug widely used for the treatment of various solid
tumors; however, its clinical use and efficacy are limited by its inherent nephrotoxicity. The …

Background Myocardial ischemia-reperfusion (MI/R) can exacerbate the initial cardiac
damage in the myocardial functional changes, including dysfunction of left ventricular …

Lysosomal-driven autophagy is a tightly controlled cellular catabolic process that breaks
down and recycles broken or superfluous cell parts. It is involved in several illnesses …

Abstract Background and Objective It is documented that low protein and amino-acid dietary
intake is related to poorer cognitive health and increased risk of dementia. Degradation of …