In the last decades, evidence suggesting the direct or indirect involvement of B cells on
multiple sclerosis (MS) pathogenesis has accumulated. The increased amount of data on …

Primary CNS lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin lymphoma that is
typically confined to the brain, eyes, and cerebrospinal fluid without evidence of systemic …

Decades of research has recognized a solid role for Pim kinases in lymphoproliferative
disorders. Often up-regulated following JAK/STAT and tyrosine kinase receptor signaling …

Safe and efficient delivery of blood-brain barrier (BBB)–impermeable cargos into the brain
through intravenous injection remains a challenge. Here, we developed a previously …

Rituximab is a mainstay in the therapy for a broad variety of B-cell malignancies. Despite its
undeniable therapeutic value, we still do not fully understand the mechanisms of action …

There is an unmet need for effective biological therapies for relapsed central nervous system
(CNS) lymphoma. Lenalidomide is active in activated B-cell type diffuse large B-cell …

Primary central nervous system lymphoma (PCNSL) is a rare form of non-Hodgkin
lymphoma that affects the brain parenchyma, spinal cord, eyes, and cerebrospinal fluid …

Background. Neutralization of central nervous system neurite growth inhibitory factors, for
example, Nogo-A, is a promising approach to improving recovery following spinal cord injury …

The brain develops and functions within a strictly controlled environment resulting from the
coordinated action of different cellular interfaces located between the blood and the …

Primary testicular lymphoma (PTL) is a rare, clinically aggressive form of extranodal
lymphoma. The vast majority of cases are histologically diffuse large B-cell lymphoma, but …