For over two decades, the minority stress model has guided research on the health of
sexually-diverse individuals (those who are not exclusively heterosexual) and gender …

An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …

Stress can influence health throughout the lifespan, yet there is little agreement about what
types and aspects of stress matter most for human health and disease. This is in part …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …

Childhood maltreatment is associated with increased risk for most forms of psychopathology.
We examine emotion dysregulation as a transdiagnostic mechanism linking maltreatment …

Despite long-standing interest in the influence of adverse early experiences on mental
health, systematic scientific inquiry into childhood adversity and developmental outcomes …

A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …