Recent advances of 5-endo-trig radical cyclization: promoting strategies and applications

Y Zhou, S Xu, X Zhang, L Zhou, H Zheng… - Chemical …, 2024 - pubs.rsc.org
5-endo-trig radical cyclization has long been recognized as one of the most straightforward
ways for the construction of densely functionalized five-membered rings. Nevertheless …

Recent advances in the synthesis of trifluoromethyl-containing heterocyclic compounds via trifluoromethyl building blocks

Y Liu, Q Tian, J Ge, X Wu, Z Li, G Cheng - Organic & Biomolecular …, 2024 - pubs.rsc.org
Trifluoromethylated heterocyclic compounds have played an increasingly significant role in
pharmaceuticals, agrochemicals, and materials. This is because the introduction of …

Metal-Free Synthesis of 2-(per) Fluoroalkyl-3-nitro Indoles via Intramolecular Cyclization of Amides

GK Sterligov, MA Rasskazova, EA Drokin… - The Journal of …, 2024 - ACS Publications
A metal-free intramolecular cyclization of N-acyl amides for the synthesis of 3-nitro-2-(per)
fluoroalkyl indoles is reported. Good functional group tolerance and a broad range of …

Recent advances in the green synthesis of indole and its derivatives using microwave irradiation and the role of indole moiety in cancer

FA Almalki, AO Baryyan - Green Chemistry Letters and Reviews, 2024 - Taylor & Francis
Indole moiety is widely present in several natural bioactive products and medicinally
important compounds. It is an essential scaffold for the development of novel leads …

Synthesis of 3‐CF3‐Indoles from HFO‐1234ze(E) via Cross‐Coupling and Intramolecular Cyclization

S Mizuno, F Yotsume, R Kasahara… - Advanced Synthesis …, 2024 - Wiley Online Library
The synthesis of indoles with a trifluoromethyl group has attracted a lot of attention because
they are promising structural subunits for pharmaceuticals and agrochemicals. As part of our …

[PDF][PDF] Reminiscing the microwave-assisted chemistry of 5-and 6-membered benzene-fused N-heterocycles

JP Soni, DG Valapil, SV Joshi, N Shankaraiah - Arkivoc, 2023 - arkat-usa.org
The dominance of N-Heterocycles' in chemical sciences, especially in drugs and
pharmacological agents, makes them fascinating to advance their sustainable chemistry …

Синтез N-гетероциклов на основе окислительной внутримолекулярной циклизации

БА Шаинян - Russian Chemical Reviews, 2022 - uspkhim.ru
Аннотация Обзор посвящен двум основным стратегиям синтеза различных N-
гетероциклов, включая соединения, содержащие гетероатомы O, S, Si, Se, Te, на …

N-Heterocycles via oxidative intramolecular cyclization

BA Shainyan - RUSSIAN CHEMICAL REVIEWS, 2022 - elibrary.ru
This review highlights two principal strategies of the last years (since 2015) for the design of
various N-heterocycles including those containing O, S, Si, Se, Te heteroatoms via oxidative …

Microwave-assisted CN formation reactions

Á Molnár - Green Sustainable Process for Chemical and …, 2021 - Elsevier
Nitrogen-containing organic compounds, in particular, heterocycles are of high importance
in numerous fields including the pharmaceutical and agrochemical industries. This review …