[Frontiers in Bioscience 13, 2400-2407, January 1, 2008] 2400 The role of chemokines in
neutrophil biology Yoshiro Kobayashi Di Page 1 [Frontiers in Bioscience 13, 2400-2407 …

The cytokine interleukin-15 (IL-15) has a key role in promoting survival, proliferation and
activation of natural killer (NK) and CD8+ T cells. Despite its functional similarities to IL-2, IL …

Mesenchymal stem cells (MSC) establish close interactions with bone marrow sinusoids in a
putative perivascular niche. These vessels contain a large storage pool of mature …

Neutrophils are constantly produced in large numbers in the bone marrow, and the same
numbers of cells need to die within a defined time period in order to keep cellular …

Objectives. Reports on the regulation of neutrophil function by IL-6 are often conflicting.
Therapeutic inhibition of IL-6 in RA is associated with occasional neutropenia, but the …

It is now established that an excessive and sustained mobilisation of neutrophils is a
hallmark of several chronic inflammatory lung disorders, including severe obstructive lung …

Phagocytic leukocytes such as neutrophils and macrophages are essential for the innate
immune response against invading bacteria. Binding and ingestion of bacteria by these host …

Neutrophils are key pathogen exterminators of the innate immune system endowed with
oxidative and non-oxidative defense mechanisms. More recently, a more complex role for …

Stress-induced hormones can alter the inflammatory response to tissue injury; however, the
precise mechanism by which epinephrine influences inflammatory response and wound …

Chronic granulomatous disease (CGD) is an immunodeficiency caused by the lack of the
superoxide-producing phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) …