Abstract Structure-specific endonucleases (SSEs) have key roles in DNA replication,
recombination and repair, and emerging roles in transcription. These enzymes have …

DNA damage repair plays a key role in maintaining genomic stability and integrity. Flap
endonuclease 1 (FEN1) is a core protein in the base excision repair (BER) pathway and …

Repair of DNA lesions through homologous recombination promotes the establishment of
stable chromosomal interactions. Multiple helicases, topoisomerases and structure-selective …

Formaldehyde (FA) is a commercially important chemical with numerous and diverse uses.
Accordingly, occupational and environmental exposure to FA is prevalent worldwide …

Replication stress results in various forms of aberrant replication intermediates that need to
be resolved for faithful chromosome segregation. Structure-specific endonucleases (SSEs) …

As a core genetic biomolecule in ecosystems, the metabolic processes of DNA, particularly
DNA replication and damage repair, are regulated by Flap endonuclease 1 (FEN1) …

The Saccharomyces cerevisiae Mus81–Mms4 complex is a highly conserved DNA structure‐
specific endonuclease that plays essential roles in the processing of recombination …

The ribosomal DNA array in Saccharomyces cerevisiae consists of many tandem repeats
whose copy number is believed to be functionally important but highly labile. Regulatory …

Mus81 is a well‐conserved DNA structure‐specific endonuclease which belongs to the
XPF/Rad1 family of proteins that are involved in DNA nucleotide excision repair. Mus81 …

Inverted repeats (IRs) are abundant in genomes and frequently serve as substrates for
chromosomal aberrations, including gene amplification. In the early stage of amplification …