Summary At present, about 33· 9 million people worldwide have Alzheimer's disease (AD),
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …

Several theories claim that dreaming is a random by-product of REM sleep physiology and
that it does not serve any natural function. Phenomenal dream content, however, is not as …

Background The use of antidepressants in dementia accompanied by depressive symptoms
is widespread, but their clinical efficacy is uncertain. This review updates an earlier version …

A thorough understanding of the cognitive effects of antidepressant medications is essential
given their frequency of use. This meta-analysis was conducted to investigate whether …

Elderly people are more likely than younger patients to develop cognitive impairment as a
result of taking medications. This reflects age-and disease-associated changes in brain …

The present paper focuses on human studies attempting to relate sleep states to memory
processes. These studies typically present learning material to participants and then …

A doença de Alzheimer é a patologia neurodegenerativa mais freqüente associada à idade,
cujas manifestações cognitivas e neuropsiquiátricas resultam em deficiência progressiva e …

BACKGROUND AND PURPOSE: To assess the efficacy and safety of ramelteon, a selective
MT1/MT2 receptor agonist, for chronic insomnia treatment. PATIENTS AND METHODS …

We discuss several lines of evidence refuting the hypothesis that procedural or declarative
memories are processed/consolidated in sleep. One of the strongest arguments against a …

The aetiology of cognitive impairment is multifactorial; however, drugs are an important
cause of delirium and dementia. Several factors may increase the risk of drug-induced …