Impact of plasma IP-10/CXCL10 and RANTES/CCL5 levels on neurocognitive function in HIV treatment-naive patients

V Ruhanya, GB Jacobs, S Naidoo, RH Paul… - AIDS research and …, 2021 - liebertpub.com
Immune activation, which is accompanied by the production of proinflammatory cytokines, is
a strong predictor of disease progression in HIV infection. Inflammation is critical in neuronal …

HIV-1 subtype C Vpr amino acid residue 45Y and specific conserved fragments are associated with neurocognitive impairment and markers of viral load

V Ruhanya, GB Jacobs, RH Paul, JA Joska… - AIDS Research and …, 2023 - liebertpub.com
There is increasing evidence that HIV-1 viral protein R (Vpr) plays an important role in the
pathogenesis of cognitive impairment. We investigated the relationship between HIV-1 …

Asociación entre inflamación y desempeño cognitivo en adultos: Revisión sistemática en PubMed 2017-2022

P Martino, MÁ Bortoli, J Bonet… - Revista Ecuatoriana …, 2023 - scielo.senescyt.gob.ec
Introducción: El declive de las funciones cognitivas es uno de los principales cambios
negativos asociados al envejecimiento. En los últimos años creció el interés por determinar …

Proinflammatory cytokines and chemokines are related to MRI measures of white and gray matter in HIV infection

V Ruhanya, GB Jacobs, R Paul, J Joska, S Seedat… - 2021 - preprints.org
Background: HIV is accompanied by production of proinflammatory cytokines which are
regarded as critical in neuronal damage, leading to brain dysfunction, hence the need to …

Treatment of trauma associated cognitive dysfunction using mesenchymal stem cell apoptotic bodies and compositions thereof

S Kesari, T Ichim, T Dixon, K O'connor… - US Patent App. 18 …, 2023 - Google Patents
Disclosed are means, treatments and compositions of matter useful for treatment of
chemotherapy/radiotherapy associated cognitive dysfunction. In one embodiment the …