Damage of the endothelial glycocalyx, which ranges from 200 to 2000 nm in thickness,
decreases vascular barrier function and leads to protein extravasation and tissue oedema …

Candida albicans is an opportunistic fungal pathogen that may cause invasive infections in
immunocompromised patients, disseminating through the bloodstream to other organs. In …

Coronary blood flow applied to the endothelial lumen modulates parenchymal functions via
paracrine effectors, but the mechanism of flow sensation is unknown. We and others have …

Candida glabrata (CG) is an opportunistic fungal pathogen that initiates infection by binding
to host cells via specific lectin-like adhesin proteins. We have previously shown the …

Blood flow acts parallel to the coronary luminal endothelial surface layer (LESL) and
modulates multiple parenchymal functions via the release of paracrine agents. Evidence …

Diverse intracoronary agonists cause cardiac effects while acting on coronary endothelial
luminal membrane (CELM) receptor. Our data show: a) the presence of AT1R in isolated …

We have shown that angiotensin II (Ang II) does not diffuse across the vessel wall, remaining
intravascularly confined and acting solely on the coronary endothelial luminal membrane …

Diverse intracoronary hormones cause their cardiac effects solely via activation of their
coronary endothelial luminal membrane (CELM) receptors. To test this hypothesis for Ang II …

Zusammenfassung Laut statistischem Bundesamt sind Herz-Kreislauf-Erkrankungen in
Deutschland mit Abstand die häufigste Todesursache. Erkrankungen, wie zum Beispiel der …

Studies in perfused hearts show that flow-sensitive G-protein coupled receptors are lectinic
suggesting that flow exerts its effects by modulating the interaction between endothelial …