Recent studies have shown that the respiratory system has an extensive ability to respond to
injury and regenerate lost or damaged cells. The unperturbed adult lung is remarkably …

The respiratory system, which consists of the lungs, trachea and associated vasculature, is
essential for terrestrial life. In recent years, extensive progress has been made in defining …

Life originated in anoxia, but many organisms came to depend upon oxygen for survival,
independently evolving diverse respiratory systems for acquiring oxygen from the …

The neural crest is an excellent model to study embryonic cell migration, since cell
behaviors can be studied in vivo with advanced optical imaging and molecular intervention …

Chemotaxis refers to the directional migration of cells towards external, soluble factors along
their gradients. It is a process that is used by many different cell types during development …

The mechanisms underlying organ vascularization are not well understood. The zebrafish
intestinal vasculature forms early, is easily imaged using transgenic lines and in-situ …

Dysregulation of angiogenesis is a common feature of many disease processes. Vascular
remodeling is believed to depend on the participation of endothelial progenitor cells, but the …

This review summarizes our current knowledge on lung vasculogenesis and angiogenesis
during normal lung development and the regulation of fetal and postnatal pulmonary …

In the current study, the contribution of the major angiogenic mechanisms, sprouting and
intussusception, to vascular development in the avian lung has been demonstrated …

Wnt5a is an important factor patterning many aspects of early development, including the
lung. We find pulmonary non-canonical Wnt5a uses Ror2 to control patterning of both distal …