Peptide research has increased during the last years due to their applications as
biomarkers, therapeutic alternatives or as antigenic sub-units in vaccines. The …

We present an assessment of different approaches to predict peptide structures using
modeling tools. Several small molecule, protein, and peptide-focused methodologies were …

Cardiovascular diseases (CVDs), mainly caused by thrombosis complications, are the
leading cause of mortality worldwide, making the development of alternative treatments …

The CABANA project (Capacity Building for Bioinformatics in Latin America) was funded by
the UK's Global Challenges Research Fund in 2017 with the aim to strengthen the …

Peptides are commonly used as therapeutic agents. However, they suffer from easy
degradation and instability. Replacing natural by non-natural amino acids can avoid these …

Being widely accepted tools in computational drug search, the (Q) SAR methods have
limitations related to data incompleteness. The proteochemometrics (PCM) approach …

The development of protease-activatable drugs and diagnostics requires identifying
substrates specific to individual proteases. However, this process becomes increasingly …

The study of protein-peptide interactions is an active research field from an experimental
and computational perspective, with the latest presenting challenges to model and simulate …

abstract The study of protein-peptide interactions is an active research field from an
experimental and computational perspective, with the latest presenting challenges to model …

From the repertoire of targets, enzymes interacting with peptide substrates constitutes one of
the most interesting groups to block due to their impact as key drivers in many biological …