CD36, located on the cell membrane, transports fatty acids in response to dietary fat. It is a
critical fatty acid sensor and regulator of lipid metabolism. The interaction between CD36 …

Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is
characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy …

How intestinal microbes regulate metabolic syndrome is incompletely understood. We show
that intestinal microbiota protects against development of obesity, metabolic syndrome, and …

Visceral adipose tissue (VAT) is an important risk factor for obesity-related metabolic
disorders. Therefore, a reduction in VAT has become a key goal in obesity management …

Disruption of lymphatic lipid transport is linked to obesity and type 2 diabetes (T2D), but
regulation of lymphatic vessel function and its link to disease remain unclear. Here we show …

A cDNA for an adipocyte membrane protein, implicated in the transport of long-chain fatty
acids, was isolated by screening with a synthetic oligonucleotide derived from the amino …

Intestinal lipid transport plays a central role in fat homeostasis. Here we review the pathways
regulating intestinal absorption and delivery of dietary and biliary lipid substrates, principally …

Cells obtain FAs either from LPL-catalyzed hydrolysis of lipoprotein triglyceride or from
unesterified FFAs associated with albumin. LPL also influences uptake of esterified lipids …

Obesity is a key risk factor for metabolic and cardiovascular diseases, and although we
understand the mechanisms regulating weight and energy balance, the causes of some …

Increases in muscle energy needs activate AMPK and induce sarcolemmal recruitment of
the fatty acid (FA) translocase CD36. The resulting rises in FA uptake and FA oxidation are …