Lymphatic transport of molecules and migration of myeloid cells to lymph nodes (LNs)
continuously inform lymphocytes on changes in drained tissues. Here, using LN …

Intestinal immunity plays a pivotal role in overall immunological defenses, constructing
mechanisms against pathogens while maintaining balance with commensal microbial …

This study investigated the structure of acidic Pueraria lobata polysaccharide (a-PLP) and its
bioactive effects on intestinal function in cyclophosphamide (CY)-treated mice. The structure …

Tumor necrosis factor (TNF) receptor-2 (TNFR2) has attracted considerable interest as a
target for immunotherapy. Indeed, using oligomeric fusion proteins of single chain-encoded …

Candida tropicalis-a prevalent gut commensal fungus in healthy individuals–contributes to
intestinal health and disease. However, how commensal C. tropicalis influences intestinal …

Microorganisms inhabit the gastrointestinal tract of ruminants and regulate body metabolism
by maintaining intestinal health. The state of gastrointestinal health is influenced not only by …

Acute graft versus host disease (aGvHD) is a life-threatening complication of allogeneic
hematopoietic cell transplantation (allo-HCT) inflicted by alloreactive T cells primed in …

This study compared the efficacies of enteral cholecalciferol and/or intravenous (IV) calcitriol
administration on mesenteric lymph node (MLN) cluster-of-differentiation-4-positive (CD4+) …

Advancing novel immunotherapy strategies requires refined tools in preclinical research to
thoroughly assess drug targets, biodistribution, safety, and efficacy. Light sheet fluorescence …

Fibroblastic reticular cells (FRCs) play important roles in tolerance by producing laminin α4
(Lama4) and altering lymph node (LN) structure and function. The present study revealed …