An essential role of the intestinal epithelium is to separate luminal contents from the
interstitium, a function primarily determined by the integrity of the epithelium and the tight …

Background Acute pancreatitis creates a catabolic stress state promoting a systemic
inflammatory response and nutritional deterioration. Adequate supply of nutrients plays an …

Background The gut is implicated in the pathogenesis of acute pancreatitis (AP) and the
infectious complications of AP are commonly associated with enteric bacteria, yet whether …

Background—In patients with major trauma and burns, total enteral nutrition (TEN)
significantly decreases the acute phase response and incidence of septic complications …

Objective The gut microbiota are the main source of infections in necrotising pancreatitis. We
investigated the effect of disruption of the intestinal microbiota by a Western-type diet on …

We conducted a prospective, observational cohort study designed to compare intestinal
permeability (IP) and development of multiple organ dysfunction syndrome (MODS) in a …

Sepsis accounts for 80% of deaths from acute pancreatitis. This study aimed to investigate
early changes in intestinal permeability in patients with acute pancreatitis, and to correlate …

Over the past decades evidence has been accumulating that intestinal barrier integrity loss
plays a key role in the development and perpetuation of a variety of disease states including …

The gastrointestinal tract constitutes one of the largest sites of exposure to the outside
environment. The function of the gastrointestinal tract in monitoring and sealing the host …

The small intestine is one of the distant organs that become damaged during severe acute
pancreatitis, due to microcirculation disturbance associated with loss of fluids in the “third …