Quorum-sensing systems as targets for antivirulence therapy

T Defoirdt - Trends in microbiology, 2018 - cell.com
The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …

Microbial surface colonization and biofilm development in marine environments

H Dang, CR Lovell - Microbiology and molecular biology reviews, 2016 - Am Soc Microbiol
Biotic and abiotic surfaces in marine waters are rapidly colonized by microorganisms.
Surface colonization and subsequent biofilm formation and development provide numerous …

Bacterial quorum sensing and microbial community interactions

RG Abisado, S Benomar, JR Klaus, AA Dandekar… - MBio, 2018 - Am Soc Microbiol
Many bacteria use a cell-cell communication system called quorum sensing to coordinate
population density-dependent changes in behavior. Quorum sensing involves production of …

Quorum sensing gene regulation by LuxR/HapR master regulators in vibrios

AS Ball, RR Chaparian, JC van Kessel - Journal of bacteriology, 2017 - Am Soc Microbiol
The coordination of group behaviors in bacteria is accomplished via the cell-cell signaling
process called quorum sensing. Vibrios have historically been models for studying bacterial …

Quorum-sensing control of antibiotic resistance stabilizes cooperation in Chromobacterium violaceum

KC Evans, S Benomar, LA Camuy-Vélez… - The ISME …, 2018 - academic.oup.com
Many Proteobacteria use quorum sensing to regulate production of public goods, such as
antimicrobials and proteases, that are shared among members of a community. Public …

Cheating on cheaters stabilizes cooperation in Pseudomonas aeruginosa

Ö Özkaya, R Balbontín, I Gordo, KB Xavier - Current Biology, 2018 - cell.com
Bacterial cooperation can be disrupted by non-producers that can profit from public goods
without paying their production cost. A cheater can increase in frequency, exhausting the …

Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions

A Hsiao, J Zhu - Virulence, 2020 - Taylor & Francis
ABSTRACT The Gram-negative bacterium Vibrio cholerae is responsible for the severe
diarrheal pandemic disease cholera, representing a major global public health concern …

Facultative cheating supports the coexistence of diverse quorum-sensing alleles

S Pollak, S Omer-Bendori, E Even-Tov… - Proceedings of the …, 2016 - National Acad Sciences
Bacterial quorum sensing enables bacteria to cooperate in a density-dependent manner via
the group-wide secretion and detection of specific autoinducer molecules. Many bacterial …

Regulation of type VI secretion systems at the transcriptional, posttranscriptional and posttranslational level

JT Hespanhol, L Nóbrega-Silva… - …, 2023 - microbiologyresearch.org
Bacteria live in complex polymicrobial communities and are constantly competing for
resources. The type VI secretion system (T6SS) is a widespread antagonistic mechanism …

Quorum sensing provides a molecular mechanism for evolution to tune and maintain investment in cooperation

EL Bruger, DJ Snyder, VS Cooper… - The ISME …, 2021 - academic.oup.com
As selection frequently favors noncooperating defectors in mixed populations with
cooperators, mechanisms that promote cooperation stability clearly exist. One potential …