LM Hablitz, M Nedergaard - Journal of Neuroscience, 2021 - Soc Neuroscience
Throughout the body, lymphatic fluid movement supports critical functions including clearance of excess fluid and metabolic waste. The glymphatic system is the analog of the …
We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
The glymphatic concept along with the discovery of meningeal lymphatic vessels have, in recent years, highlighted that fluid is directionally transported within the central nervous …
TJ Lohela, TO Lilius, M Nedergaard - Nature Reviews Drug Discovery, 2022 - nature.com
In the past decade, evidence for a fluid clearance pathway in the central nervous system known as the glymphatic system has grown. According to the glymphatic system concept …
DH Kelley, JH Thomas - Annual Review of Fluid Mechanics, 2023 - annualreviews.org
Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and through the brain transports not only those water-like fluids but also any solutes they carry …
The glymphatic system is a fluid-transport system that accesses all regions of the brain. It facilitates the exchange of cerebrospinal fluid and interstitial fluid and clears waste from the …
SB Hladky, MA Barrand - Fluids and Barriers of the CNS, 2022 - Springer
The glymphatic hypothesis proposes a mechanism for extravascular transport into and out of the brain of hydrophilic solutes unable to cross the blood–brain barrier. It suggests that there …
TO Wichmann, HH Damkier… - Frontiers in human …, 2022 - frontiersin.org
A comprehensive understanding of the cerebrospinal fluid (CSF) system is essential for our understanding of health and disease within the central nervous system (CNS). The system of …
KAS Boster, S Cai… - Proceedings of the …, 2023 - National Acad Sciences
Quantifying the flow of cerebrospinal fluid (CSF) is crucial for understanding brain waste clearance and nutrient delivery, as well as edema in pathological conditions such as stroke …