International union of basic and clinical pharmacology CXIII: Nuclear receptor superfamily—Update 2023
The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …
gene network programs involved in a wide range of physiologic processes. This review will …
Breast cancer, screening and diagnostic tools: All you need to know
D Barba, A León-Sosa, P Lugo, D Suquillo… - Critical reviews in …, 2021 - Elsevier
Breast cancer is one of the most frequent malignancies among women worldwide. Methods
for screening and diagnosis allow health care professionals to provide personalized …
for screening and diagnosis allow health care professionals to provide personalized …
The role of sex hormones and steroid receptors on female reproductive cancers
LG de Almeida Chuffa, LA Lupi-Júnior, AB Costa… - Steroids, 2017 - Elsevier
Sex steroids have been widely described to be associated with a number of human
diseases, including hormone-dependent tumors. Several studies have been concerned …
diseases, including hormone-dependent tumors. Several studies have been concerned …
Pannexin 1 drives efficient epithelial repair after tissue injury
Epithelial tissues such as lung and skin are exposed to the environment and therefore
particularly vulnerable to damage during injury or infection. Rapid repair is therefore …
particularly vulnerable to damage during injury or infection. Rapid repair is therefore …
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system
Background: Metastatic outgrowth in breast cancer can occur years after a seeming cure.
Existing model systems of dormancy are limited as they do not recapitulate human …
Existing model systems of dormancy are limited as they do not recapitulate human …
Estrogen receptor α dependent regulation of estrogen related receptor β and its role in cell cycle in breast cancer
B Madhu Krishna, S Chaudhary, DR Mishra, SK Naik… - BMC cancer, 2018 - Springer
Background Breast cancer (BC) is highly heterogeneous with~ 60–70% of estrogen receptor
positive BC patient's response to anti-hormone therapy. Estrogen receptors (ERs) play an …
positive BC patient's response to anti-hormone therapy. Estrogen receptors (ERs) play an …
Systems-level effects of ectopic galectin-7 reconstitution in cervical cancer and its microenvironment
JC Higareda-Almaraz, JS Ruiz-Moreno, J Klimentova… - BMC cancer, 2016 - Springer
Abstract Background Galectin-7 (Gal-7) is negatively regulated in cervical cancer, and
appears to be a link between the apoptotic response triggered by cancer and the anti …
appears to be a link between the apoptotic response triggered by cancer and the anti …
NEDDylation negatively regulates ERRβ expression to promote breast cancer tumorigenesis and progression
Estrogen-related receptor beta (ERRβ) is downregulated in breast cancer cells and its
overexpression in breast cancer patients is positively correlated with an improved prognosis …
overexpression in breast cancer patients is positively correlated with an improved prognosis …
Overexpression of caspase 7 is ERα dependent to affect proliferation and cell growth in breast cancer cells by targeting p21Cip
Abstract Caspase 7 (CASP7) expression has important function during cell cycle
progression and cell growth in certain cancer cells and is also involved in the development …
progression and cell growth in certain cancer cells and is also involved in the development …
Transcriptomics and metabolomics integration reveals redox-dependent metabolic rewiring in breast cancer cells
Simple Summary Metabolic rewiring fuels cancer proliferation by enhanced glycolysis and
the increased NADH/NAD+ ratio. In this study, we highlight the critical role of NADH in the …
the increased NADH/NAD+ ratio. In this study, we highlight the critical role of NADH in the …