Short chain fatty acids: key regulators of the local and systemic immune response in inflammatory diseases and infections

LM Ney, M Wipplinger, M Grossmann… - Open …, 2023 - royalsocietypublishing.org
The human intestinal microbiome substantially affects human health and resistance to
infections in its dynamic composition and varying release of microbial-derived metabolites …

[HTML][HTML] Role of microbiota short-chain fatty acids in the pathogenesis of autoimmune diseases

A Rasouli-Saravani, K Jahankhani, S Moradi… - Biomedicine & …, 2023 - Elsevier
There is emerging evidence that microbiota and its metabolites play an important role in
helath and diseases. In this regard, gut microbiota has been found as a crucial component …

[HTML][HTML] The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials

H Duan, LJ Wang, M Huangfu, H Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Short-chain fatty acids (SCFAs) derived from the fermentation of carbohydrates by gut
microbiota play a crucial role in regulating host physiology. Among them, acetate …

[HTML][HTML] Metabolites as extracellular vesicle cargo in health, cancer, pleural effusion, and cardiovascular diseases: An emerging field of study to diagnostic and …

Y Zhang, F Liang, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Extracellular vesicles (EVs) are highly diverse nanoscale membrane-bound structures
released from different cell types into the extracellular environment. They play essential …

Coronavirus disease 2019 (COVID‐19) update: From metabolic reprogramming to immunometabolism

M Rudiansyah, SA Jasim… - Journal of Medical …, 2022 - Wiley Online Library
The field of immunometabolism investigates and describes the effects of metabolic rewiring
in immune cells throughout activation and the fates of these cells. Recently, it has been …

The emerging role of microbiota-derived short-chain fatty acids in immunometabolism

SA Jasim, MJC Opulencia, AA Ramírez-Coronel… - International …, 2022 - Elsevier
The accumulating evidence revealed that microbiota plays a significant function in training,
function, and the induction of host immunity. Once this interaction (immune system …

[HTML][HTML] Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics

Z Payandeh, B Tangruksa, J Synnergren… - Molecular Aspects of …, 2024 - Elsevier
Modern methods of molecular diagnostics and therapy have revolutionized the field of
medicine in recent years by providing more precise and effective tools for detecting and …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

Cellular metabolism hijacked by viruses for immunoevasion: potential antiviral targets

J Li, Y Wang, H Deng, S Li, HJ Qiu - Frontiers in Immunology, 2023 - frontiersin.org
Cellular metabolism plays a central role in the regulation of both innate and adaptive
immunity. Immune cells utilize metabolic pathways to modulate the cellular differentiation or …

[HTML][HTML] A Comprehensive Review of the Triangular Relationship among Diet–Gut Microbiota–Inflammation

N Randeni, M Bordiga, B Xu - International Journal of Molecular Sciences, 2024 - mdpi.com
The human gastrointestinal tract hosts a complex and dynamic community of
microorganisms known as the gut microbiota, which play a pivotal role in numerous …