Indium (III) as π-acid catalyst for the electrophilic activation of carbon–carbon unsaturated systems

JP Sestelo, LA Sarandeses, MM Martínez… - Organic & …, 2018 - pubs.rsc.org
This review focuses on the utilization of indium (III) as π-acid for the activation of C–C
unsaturated bonds in organic synthesis. In addition to its well-known σ-coordination with …

Mechanism to model: a physical organic chemistry approach to reaction prediction

JP Reid, IO Betinol, Y Kuang - Chemical Communications, 2023 - pubs.rsc.org
The application of mechanistic generalizations is at the core of chemical reaction
development and application. These strategies are rooted in physical organic chemistry …

Electrochemical synthesis of selenyl-dihydrofurans via anodic selenofunctionalization of allyl-naphthol/phenol derivatives and their anti-Alzheimer activity

MR Scheide, AR Schneider, GAM Jardim… - Organic & …, 2020 - pubs.rsc.org
Herein, we report an eco-friendly, electrosynthetic approach for the intramolecular
oxyselenylation of allyl-naphthol/phenol derivatives. This reaction proceeds with 0.2 equiv …

Alkynes and nitrogen compounds: useful substrates for the synthesis of pyrazoles

JSS Neto, G Zeni - Chemistry–A European Journal, 2020 - Wiley Online Library
The easy preparation and functionalization of pyrazoles associated with their innumerable
biological properties have made this class of N‐heterocycles very attractive for the …

Synthetic and biosynthetic methods for selective cyclisations of 4, 5-epoxy alcohols to tetrahydropyrans

JI Bowen, L Wang, MP Crump, CL Willis - Organic & Biomolecular …, 2022 - pubs.rsc.org
Tetrahydropyrans (THPs) are common structural motifs found in natural products and
synthetic therapeutic molecules. In Nature these 6-membered oxygen heterocycles are often …

Facile synthesis of diiodoheteroindenes and understanding their Sonogashira cross-coupling selectivity for the construction of unsymmetrical enediynes

AV Ponomarev, NA Danilkina, JS Okuneva… - Organic & …, 2024 - pubs.rsc.org
Electrophile-promoted cyclizations of functionalized alkynes offer a useful tool for
constructing halogen-substituted heterocycles primed for further derivatization …

MOF-Zn-NHC as an efficient N-heterocyclic carbene catalyst for aerobic oxidation of aldehydes to their corresponding carboxylic acids via a cooperative geminal …

S Babaee, M Zarei, MA Zolfigol - RSC advances, 2021 - pubs.rsc.org
As an efficient heterogenous N-heterocyclic carbene (NHC) catalyst, MOF-Zn-NHC was
used in the aerobic oxidation of aryl aldehydes to their corresponding carbocyclic acids via …

Ambruticins: tetrahydropyran ring formation and total synthesis

JI Bowen, L Wang, MP Crump, CL Willis - Organic & Biomolecular …, 2021 - pubs.rsc.org
The ambruticins are a family of polyketide natural products which exhibit potent antifungal
activity. Gene knockout experiments are in accord with the proposal that the tetrahydropyran …

Radical Cyclization of Ynamides to Nitrogen Heterocycles

C Zhang, N Blanchard, G Evano - Synthesis, 2023 - thieme-connect.com
An efficient radical cyclization of suitably functionalized ynamides to nitrogen-containing
heterocycles is reported. Upon reaction with tributyltin hydride in the presence of catalytic …

Construction of piperidine-2, 4-dione-type azaheterocycles and their application in modern drug development and natural product synthesis

RM Tikhov, NY Kuznetsov - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
The current review summarizes the latest achievements in the synthesis of piperidine-2, 4-
dione-type azaheterocycles. Two main groups traditional (carbonyl compound …