Colon cancer continues to be one of the leading causes of mortality and morbidity
throughout the world despite the availability of reliable screening tools and effective …

Simple Summary In patients with stage III colon cancer, adjuvant chemotherapy with a
fluoropyrimidine combined with oxaliplatin reduces the risk of recurrence and mortality, with …

PURPOSE To develop recommendations for adjuvant therapy for patients with resected
stage II colon cancer. METHODS ASCO convened an Expert Panel to conduct a systematic …

Background T stage is a prognostic biomarker for overall survival in colon cancer and
pathologic T4 disease is a high-risk characteristic. Adjuvant chemotherapy is recommended …

This study aimed to validate the prognostic value of Immunoscore (IS) in stage II colorectal
cancer (CRC), and explore the roles of IS and circulating tumor DNA (ctDNA) in the adjuvant …

Simple Summary Stage II colon cancer is defined as an early stage of the tumor disease,
without the involvement of lymph nodes or distant organs. In this group of patients, surgery …

The main therapeutic options for colorectal cancer are surgical resection and adjuvant
chemotherapy in non-metastatic disease. However, the evaluation of the overall adjuvant …

Routine tumor-node-metastasis (TNM) staging of colorectal cancer is imperfect in predicting
survival due to tumor pathobiological heterogeneity and imprecise assessment of tumor …

Background Serum carcinoembryonic antigen (CEA) is an important biomarker for
diagnosis, prognosis, recurrence, metastasis monitoring, and the evaluation of the effect of …

Aim The aim was to assess the benefit of adjuvant chemotherapy in high‐risk Stage II
colorectal cancer. Method A systematic literature review and meta‐analysis was performed …