Diffusion MRI (dMRI) is a unique tool for the study of brain circuitry, as it allows us to image
both the macroscopic trajectories and the microstructural properties of axon bundles in vivo …

Phantoms, both numerical (software) and physical (hardware), can serve as a gold standard
for the validation of MRI methods probing the brain microstructure. This review aims to …

Background The g-ratio, quantifying the comparative thickness of the myelin sheath
encasing an axon, is a geometrical invariant that has high functional relevance because of …

The g‐ratio, defined as the inner‐to‐outer diameter of a myelinated axon, is associated with
the speed of nerve impulse conduction, and represents an index of axonal myelination and …

Conduction velocity is the speed at which electrical signals travel along axons and is a
crucial determinant of neural communication. Inferences about conduction velocity can now …

Introduction Quantitative and non-invasive measures of brain myelination and maturation
during development are of great importance to both clinical and translational research …

Activity-dependent myelination is a fundamental mode of brain plasticity which significantly
influences network function. We recently discovered that absence seizures, which occur in …

Biophysical diffusion‐weighted imaging (DWI) models are increasingly used in
neuroscience to estimate the axonal water fraction (f AW), which in turn is key for …

Diffusion MRI is a valuable tool for probing tissue microstructure in the brain noninvasively.
Today, model-based techniques are widely available and used for white matter …

The myelin concentration and the degree of myelination of nerve fibers can provide valuable
information on the integrity of human brain tissue. Magnetic resonance imaging (MRI) of …