[HTML][HTML] Heterogeneity and plasticity of cancer-associated fibroblasts in the pancreatic tumor microenvironment
LNC Boyd, KD Andini, GJ Peters, G Kazemier… - Seminars in cancer …, 2022 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a notably poor
prognosis, in urgent need of improved treatment strategies. The desmoplastic PDAC tumor …
prognosis, in urgent need of improved treatment strategies. The desmoplastic PDAC tumor …
[HTML][HTML] Collagen code in tumor microenvironment: functions, molecular mechanisms, and therapeutic implications
Q Zhang, ZY An, W Jiang, WL Jin, XY He - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The tumor microenvironment (TME) is crucial in cancer progression, and the extracellular
matrix (ECM) is an important TME component. Collagen is a major ECM component that …
matrix (ECM) is an important TME component. Collagen is a major ECM component that …
Force-dependent extracellular matrix remodeling by early-stage cancer cells alters diffusion and induces carcinoma-associated fibroblasts
It is known cancer cells secrete cytokines inducing normal fibroblasts (NFs) to become
carcinoma-associated fibroblasts (CAFs). However, it is not clear how the CAF-promoting …
carcinoma-associated fibroblasts (CAFs). However, it is not clear how the CAF-promoting …
Plant extract from Caesalpinia spinosa inhibits cancer-associated fibroblast-like cells generation and function in a tumor microenvironment model
Interactions in the tumor microenvironment (TME) between tumor cells and stromal cells
such as cancer-associated fibroblasts (CAF) favor increased survival, progression, and …
such as cancer-associated fibroblasts (CAF) favor increased survival, progression, and …
[HTML][HTML] Deletion of IKKβ in activated fibroblasts promotes tumor progression in melanoma
S Zhang, M Harada, T Kimura, N Ashida - Biochemical and Biophysical …, 2022 - Elsevier
Cancer-associated fibroblasts (CAFs) are a major component of the tumor microenvironment
and play critical roles in tumorigenesis. CAFs consists of multiple subpopulations, which …
and play critical roles in tumorigenesis. CAFs consists of multiple subpopulations, which …