Mechanistic landscape of membrane-permeabilizing peptides

S Guha, J Ghimire, E Wu, WC Wimley - Chemical reviews, 2019 - ACS Publications
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

Antimicrobial peptides (AMPs): roles, functions and mechanism of action

R Seyfi, FA Kahaki, T Ebrahimi… - International Journal of …, 2020 - Springer
Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of
living organisms. In fact, AMPs have ability to incite the innate immune response and combat …

A review of the latest advances in encrypted bioactive peptides from protein-rich waste

AC Lemes, L Sala, JC Ores, ARC Braga… - International journal of …, 2016 - mdpi.com
Bioactive peptides are considered the new generation of biologically active regulators that
not only prevent the mechanism of oxidation and microbial degradation in foods but also …

Mycobacterium tuberculosis cell-wall and antimicrobial peptides: a mission impossible?

YM Jacobo-Delgado, A Rodríguez-Carlos… - Frontiers in …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …

Scorpions from Mexico: From species diversity to venom complexity

CE Santibáñez-López, OF Francke, C Ureta… - Toxins, 2015 - mdpi.com
Scorpions are among the oldest terrestrial arthropods, which are distributed worldwide,
except for Antarctica and some Pacific islands. Scorpion envenomation represents a public …

Polypharmacological cell-penetrating peptides from venomous marine animals based on immunomodulating, antimicrobial, and anticancer properties

S Hemmati, H Rasekhi Kazerooni - Marine Drugs, 2022 - mdpi.com
Complex pathological diseases, such as cancer, infection, and Alzheimer's, need to be
targeted by multipronged curative. Various omics technologies, with a high rate of data …

Antimicrobial activity developed by scorpion venoms and its peptide component

CA Rincón-Cortés, MA Bayona-Rojas… - Toxins, 2022 - mdpi.com
Microbial infections represent a problem of great importance at the public health level, with a
high rate of morbidity-mortality worldwide. However, treating the different diseases …

Metal–peptide complexes as promising antibiotics to fight emerging drug resistance: New perspectives in tuberculosis

C Di Natale, I De Benedictis, A De Benedictis… - Antibiotics, 2020 - mdpi.com
In metal-peptide interactions, cations form stable complexes through bonds with
coordinating groups as side chains of amino acids. These compounds, among other things …

Antimicrobial peptides as potential anti-tubercular leads: a concise review

GS Oliveira, RP Costa, P Gomes, MS Gomes, T Silva… - Pharmaceuticals, 2021 - mdpi.com
Despite being considered a public health emergency for the last 25 years, tuberculosis (TB)
is still one of the deadliest infectious diseases, responsible for over a million deaths every …

Antimicrobial peptides as drugs with double response against Mycobacterium tuberculosis coinfections in lung cancer

G Polinário, LMDG Primo, MABC Rosa… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis and lung cancer are, in many cases, correlated diseases that can be confused
because they have similar symptoms. Many meta-analyses have proven that there is a …