A defining characteristic of the brain is its remarkable capacity to undergo activity-dependent
functional and morphological remodeling via mechanisms of plasticity that form the basis of …

Whole Brain Emulation: A Roadmap Page 1 Whole Brain Emulation A Roadmap (2008)
Technical Report #2008-3 Anders Sandberg* Nick Bostrom Future of Humanity Institute …

Environmental manipulations can enhance neuroplasticity in the brain, with enrichment‐
induced cognitive improvements being linked to increased expression of growth factors …

Alzheimer's disease (AD) is increasingly referred to as a “synaptopathy.” This moniker
reflects the loss or damage of synapses that occurs as the disease progresses, which in turn …

A variety of classic psychedelics and MDMA have been shown to enhance fear extinction in
rodent models. This has translational significance because a standard treatment for post …

Abstract Background Perioperative neurocognitive disorders (PNDs) are considered the
most common postoperative complication in geriatric patients. However, its pathogenesis is …

Structural changes in brain circuits active during learning are thought to be important for
long-term memory storage. If these changes support long-term information storage, they …

Aggregation of the amyloid β-protein (Aβ) is believed to play a central role in initiating the
molecular cascade that culminates in Alzheimer-type dementia (AD), a disease which in its …

Extensive research has implicated the amyloid-β protein (Aβ) in the aetiology of Alzheimer's
disease (AD). This protein has been shown to produce memory deficits when injected into …

Injury to the anterior thalamic nuclei (ATN) may affect both hippocampus and retrosplenial
cortex thus explaining some parallels between diencephalic and medial temporal lobe …